SCHEMBL607222

SCHEMBL607222

C=C(c1ccccc1)c1ccc(N(C)C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 1.00
MEN1 O00255 2/20 1.00
RAB9A P51151 6/20 0.64
HPGD P15428 4/20 0.64
NPC1 O15118 3/20 0.64
ALDH1A1 P00352 9/20 0.60
GFER P55789 1/20 0.60
MAPT P10636 6/20 0.50
KCNK3 O14649 1/20 0.49
KDM4E B2RXH2 1/20 0.49
TSHR P16473 3/20 0.48
MAPK1 P28482 3/20 0.48
ALOX15 P16050 2/20 0.48
CYP3A4 P08684 1/20 0.48
HBB P68871 1/20 0.48
HSD17B10 Q99714 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
CASP3 P42574 1/20 0.47
CYP1B1 Q16678 1/20 0.47
SENP8 Q96LD8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441802 0.91 MEN1 (0.83) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL12679042 0.91 MEN1 (0.83) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL30289908 0.89 KMT2A (0.79) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL17811466 0.88 MEN1 (0.78) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL10473921 0.84 KMT2A (0.72) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL9099853 0.83 MEN1 (0.70) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL10473987 0.83 MEN1 (0.70) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL24851242 0.82 RAB9A (0.69) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL5339984 0.82 RAB9A (0.69) KMT2AMEN1RAB9AHPGDNPC1
SCHEMBL609636 0.82 KMT2A (0.69) KMT2AMEN1RAB9AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113980215-B HIPS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN claimed
CN-113999355-B HIPS resin containing DPE derivative, butadiene and styrene star copolymer blocks and preparation method thereof 大连理工大学 2023-04-28 CN claimed
CN-113831478-B ABS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN claimed
CN-113980214-B ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN claimed
CN-113912798-B Star block copolymer based on DPE derivatives, butadiene, isoprene and styrene monomers and preparation method thereof 大连理工大学 2023-03-24 CN claimed
CN-113817111-B Soluble polymerized A-DPE derivative SIBR star-shaped integrated rubber toughened HIPS resin and preparation method thereof 大连理工大学 2022-11-11 CN claimed
CN-113698543-B Soluble polymerized A-DPE derivative SIBR integrated rubber toughened ABS resin and preparation method thereof 大连理工大学 2022-09-23 CN claimed
EP-3357943-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD OF PREPARING THE SAME LG CHEMICAL LTD (KR) 2022-07-20 EP claimed
CN-114213596-A HIPS (high impact polystyrene) resin toughened by rubber integrated with solution polymerized A-DPE (Polyacrylamide-DPE) derivatives and preparation method thereof 大连理工大学 2022-03-22 CN claimed
CN-113999355-A HIPS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-02-01 CN claimed
CN-113980215-A HIPS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-01-28 CN claimed
CN-113980214-A ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-01-28 CN claimed
US-11066487-B2 Modified conjugated diene-based polymer and method of preparing the same LG CHEM, LTD. 2021-07-20 US claimed
US-20210102055-A1 POLYMER COMPOSITION FOR 3D PRINTING, MATERIAL, METHOD AND MOLDED ARTICLE THEREOF TSRC CORPORATION (TW) 2021-04-08 US claimed
US-10450387-B2 Modifier, modified and conjugated diene-based polymer and methods for preparing them LG CHEM, LTD. (KR) 2019-10-22 US claimed
US-20180371113-A1 MODIFIER, MODIFIED AND CONJUGATED DIENE-BASED POLYMER AND METHODS FOR PREPARING THEM LG CHEM, LTD. (KR) 2018-12-27 US claimed
US-20180371114-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD OF PREPARING THE SAME LG CHEM, LTD. (KR) 2018-12-27 US claimed
EP-3372622-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING SAME LG Chem, Ltd. (KR) 2018-09-12 EP claimed
EP-3357943-A1 MODIFIER AND MODIFIED CONJUGATED DIENE BASED POLYMER, AND PREPARATION METHODS THEREFOR LG Chem, Ltd. (KR) 2018-08-08 EP claimed
US-4975491-A Functionalized polymers prepared by anionic polymerization THE DOW CHEMICAL COMPANY (US) 1990-12-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066487-B2 Modified conjugated diene-based polymer and method of preparing the same FDFT1, DCLRE1A, DYNLL1 KMT2A 1361/4885MEN1 391/4885RAB9A 3416/4885
US-10450387-B2 Modifier, modified and conjugated diene-based polymer and methods for preparing them UFM1, F13A1, ITGAM KMT2A 2160/4885MEN1 1219/4885RAB9A 4416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.