Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4949271 | 0.98 | OPRM1 (0.43) | OPRM1SPHK1TP53LAP3GRIK1 | |
| Bromide SCHEMBL4950781 | 0.98 | OPRM1 (0.43) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL3306797 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL4946939 | 0.96 | OPRM1 (0.44) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL4953435 | 0.96 | OPRM1 (0.44) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL4951435 | 0.96 | OPRM1 (0.44) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL4951440 | 0.96 | OPRM1 (0.44) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL11897441 | 0.96 | OPRM1 (0.44) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL3345884 | 0.91 | OPRM1 (0.37) | OPRM1SPHK1TP53GRIK1GRIK2 | |
| SCHEMBL3309835 | 0.89 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7880024-B2 | Ionic liquids miscible with various polar/non-polar solvents and method of preparing the same | SAMSUNG ENGINEERING CO., LTD. (KR) | 2011-02-01 | — | — | US | disclosed |
| US-20090253924-A1 | Ionic liquids miscible with various polar/non-polar solvents and method of preparing the same | SAMSUNG ENGINEERING CO., LTD. (KR) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253924-A1 | Ionic liquids miscible with various polar/non-polar solvents and method of preparing the same | PIP5K1B, PIP4K2B, PIP4K2C | OPRM1 1227/4885SPHK1 2282/4885TP53 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.