Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679919 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HTTFOLH1RAB9ASMN1; SMN2 | |
| SCHEMBL12679903 | 0.95 | FOLH1 (0.40) | ALDH1A1HTTFOLH1RAB9ASMN1; SMN2 | |
| SCHEMBL1114717 | 0.87 | FOLH1 (0.46) | ALDH1A1HTTFOLH1RAB9ASMN1; SMN2 | |
| SCHEMBL1114866 | 0.87 | FOLH1 (0.46) | ALDH1A1HTTFOLH1RAB9ASMN1; SMN2 | |
| SCHEMBL1114990 | 0.87 | FOLH1 (0.46) | ALDH1A1HTTFOLH1RAB9ASMN1; SMN2 | |
| SCHEMBL1114975 | 0.87 | FOLH1 (0.46) | ALDH1A1HTTFOLH1RAB9ASMN1; SMN2 | |
| SCHEMBL12679928 | 0.86 | DRD4 (0.42) | ALDH1A1HTTFOLH1RAB9ALMNA | |
| SCHEMBL12679864 | 0.86 | DRD4 (0.42) | ALDH1A1HTTFOLH1RAB9ALMNA | |
| SCHEMBL12679935 | 0.86 | FOLH1 (0.52) | ALDH1A1FOLH1LMNAKDM4EPOLB | |
| SCHEMBL12679939 | 0.86 | DRD4 (0.42) | ALDH1A1HTTFOLH1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273794-B2 | 7-[isopropyl(phenyl)amino]-7-oxoheptanoic acid, 3-(2-Hydroxy-benzoylamino)-butyric acid, 4-Oxo-4-phenyl-butyric acid, 10-(2-Hydroxy-phenyl)-10-oxo-decanoic acid, 4-(4-Methoxy-phenyl)-4-oxo-butyric acid: promoting the absorption of the active agent | EMISPHERE TECHNOLOGIES, INC. (US) | 2012-09-25 | — | — | US | disclosed |