Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679837 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL13468805 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL12679943 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL12679838 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL12856049 | 0.95 | ALDH1A1 (0.61) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL1114800 | 0.89 | ALDH1A1 (0.61) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL1114834 | 0.89 | ALDH1A1 (0.61) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL1114760 | 0.89 | ALDH1A1 (0.61) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL1114751 | 0.89 | ALDH1A1 (0.61) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL11815719 | 0.88 | ALDH1A1 (0.59) | ALDH1A1LMNATP53SMN1; SMN2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273794-B2 | 7-[isopropyl(phenyl)amino]-7-oxoheptanoic acid, 3-(2-Hydroxy-benzoylamino)-butyric acid, 4-Oxo-4-phenyl-butyric acid, 10-(2-Hydroxy-phenyl)-10-oxo-decanoic acid, 4-(4-Methoxy-phenyl)-4-oxo-butyric acid: promoting the absorption of the active agent | EMISPHERE TECHNOLOGIES, INC. (US) | 2012-09-25 | — | — | US | disclosed |