Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268308 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL17806131 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL1332901 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL27873025 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP1A2KMT2AMEN1FFAR1 | |
| SCHEMBL5787453 | 0.80 | ALDH1A1 (0.68) | ALDH1A1CYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL5787444 | 0.80 | ALDH1A1 (0.68) | ALDH1A1CYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL17806132 | 0.79 | ALDH1A1 (0.58) | ALDH1A1CYP1A2KMT2AMEN1PDE10A | |
| SCHEMBL29596733 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1FFAR1NPC1 | |
| SCHEMBL4772795 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL7038588 | 0.78 | ALDH1A1 (0.65) | ALDH1A1CYP1A2TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | GSK3B, GSK3A, GSKIP | ALDH1A1 1585/4885CYP1A2 1261/4885TSHR 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.