Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372096 | 1.00 | HCRTR1 (0.37) | HCRTR1HCRTR2PREPDGAT1AADAT | |
| SCHEMBL12682992 | 0.89 | HCRTR1 (0.39) | HCRTR1HCRTR2PREPAADATTMEM97 | |
| SCHEMBL12683007 | 0.84 | PRCP (0.43) | — | |
| SCHEMBL12683244 | 0.81 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL2631645 | 0.77 | PRCP (0.51) | — | |
| SCHEMBL6126944 | 0.77 | PRCP (0.51) | — | |
| SCHEMBL13309251 | 0.77 | PRCP (0.51) | — | |
| SCHEMBL12682914 | 0.76 | NR1H2 (0.37) | HCRTR1HCRTR2PREPAADATTMEM97 | |
| SCHEMBL8748850 | 0.76 | PRCP (0.52) | — | |
| SCHEMBL15373561 | 0.76 | HDAC1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050918-A2 | TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICAL, INC. (US) | 2012-04-19 | — | — | WO | disclosed |