Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12683007 | 0.89 | PRCP (0.43) | PRCPGPR119 | |
| SCHEMBL15373639 | 0.86 | ABCB1 (0.35) | HCRTR1HCRTR2PRMT5CHEK2PRCP | |
| SCHEMBL12682992 | 0.84 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL12683231 | 0.83 | PRMT5 (0.38) | HCRTR1HCRTR2PRMT5CHEK2PRCP | |
| SCHEMBL12683162 | 0.81 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL15372096 | 0.81 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL12683161 | 0.80 | KMT2A (0.38) | HCRTR1HCRTR2CHEK2GPR119 | |
| SCHEMBL15373561 | 0.79 | HDAC1 (0.36) | PRMT5 | |
| SCHEMBL15443427 | 0.79 | PRCP (0.51) | HCRTR1HCRTR2PRCP | |
| SCHEMBL12683153 | 0.78 | HCRTR1 (0.35) | HCRTR1HCRTR2PRMT5CHEK2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050918-A2 | TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICAL, INC. (US) | 2012-04-19 | — | — | WO | disclosed |