Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269265 | 0.84 | HDAC1 (0.51) | HTT | |
| SCHEMBL1269221 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2ALOX15RAB9ANPC1KMT2A | |
| SCHEMBL1269667 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2ALOX15RAB9ANPC1KMT2A | |
| SCHEMBL1269283 | 0.80 | POLB (0.62) | SMN1; SMN2ALOX15RAB9ANPC1KMT2A | |
| SCHEMBL29460273 | 0.78 | SMN1; SMN2 (0.79) | SMN1; SMN2ALOX15RAB9ANPC1KMT2A | |
| SCHEMBL21065524 | 0.78 | SMN1; SMN2 (0.79) | SMN1; SMN2ALOX15RAB9ANPC1KMT2A | |
| SCHEMBL26686375 | 0.77 | JAK2 (0.57) | SMN1; SMN2KMT2AHTT | |
| SCHEMBL1269305 | 0.77 | RAB9A (0.54) | SMN1; SMN2ALOX15RAB9ANPC1KMT2A | |
| SCHEMBL11618998 | 0.76 | RAB9A (1.00) | SMN1; SMN2ALOX15RAB9ANPC1KMT2A | |
| SCHEMBL26686525 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | GSK3B, GSK3A, GSKIP | SMN1; SMN2 865/4885ALOX15 4220/4885RAB9A 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.