Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAC2 | P15153 | 1/20 | 0.34 |
| ▸ | RAC3 | P60763 | 1/20 | 0.34 |
| ▸ | CDC42 | P60953 | 1/20 | 0.34 |
| ▸ | RAC1 | P63000 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12685757 | 0.92 | L3MBTL1 (0.44) | KDM4EATML3MBTL1KMT2AHDAC4 | |
| SCHEMBL12685769 | 0.91 | KDM4E (0.39) | KDM4EATML3MBTL1KMT2AHDAC4 | |
| SCHEMBL12685975 | 0.90 | KDM4E (0.33) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL20161062 | 0.88 | L3MBTL1 (0.47) | KDM4EATML3MBTL1KMT2AHDAC4 | |
| SCHEMBL12685759 | 0.87 | L3MBTL1 (0.40) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL12685822 | 0.86 | KDM4E (0.36) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL22143567 | 0.86 | PTGER4 (0.34) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL24677153 | 0.86 | L3MBTL1 (0.45) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL24677163 | 0.86 | L3MBTL1 (0.49) | KDM4EATML3MBTL1RAC2RAC3 | |
| SCHEMBL24677071 | 0.86 | L3MBTL1 (0.51) | KDM4EATML3MBTL1RAC2RAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |