Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.74 |
| ▸ | MAOB | P27338 | 3/20 | 0.74 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.74 |
| ▸ | CES1 | P23141 | 2/20 | 0.68 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353311 | 1.00 | MAOA (0.74) | MAOAMAOBCYP2A6CES1PBRM1 | |
| SCHEMBL24746 | 1.00 | MAOA (0.74) | MAOAMAOBCYP2A6CES1PBRM1 | |
| SCHEMBL16552853 | 0.97 | MAOA (0.71) | MAOAMAOBCYP2A6CES1PBRM1 | |
| Benzene SCHEMBL28357254 | 0.97 | MAOB (0.71) | MAOAMAOBCYP2A6CES1PBRM1 | |
| Bromide SCHEMBL28903594 | 0.97 | MAOA (0.71) | MAOAMAOBCYP2A6CES1PBRM1 | |
| SCHEMBL31454252 | 0.97 | MAOA (0.71) | MAOAMAOBCYP2A6CES1PBRM1 | |
| Hydrochloric Acid SCHEMBL28796491 | 0.97 | MAOA (0.71) | MAOAMAOBCYP2A6CES1PBRM1 | |
| Biphenyl SCHEMBL3089519 | 0.91 | MAOB (0.63) | MAOAMAOBCYP2A6CES1PBRM1 | |
| SCHEMBL5105222 | 0.91 | MAOB (0.63) | MAOAMAOBCYP2A6CES1PBRM1 | |
| SCHEMBL5050048 | 0.91 | MAOA (0.91) | MAOAMAOBCYP2A6CES1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884109-B2 | immunosuppressants such as 2-(6-Fluoro-1H-benzo[d]imidazol-1-yl)-9-((1R,4R)-4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)-7H-purin-8(9H)-one, used for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection | WYETH LLC (US) | 2011-02-08 | — | — | US | disclosed |
| US-20080287468-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| WO-2000009659-A1 | METHOD FOR PRODUCING INDANE DERIVATIVES | LONZA AG (CH) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287468-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | TPMT, P2RY4, P2RY1 | MAOA 1365/4885MAOB 943/4885CYP2A6 1334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.