⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668197 | 0.68 | — | — | |
| SCHEMBL225335 | 0.62 | — | — | |
| SCHEMBL1268892 | 0.62 | — | — | |
| SCHEMBL4932232 | 0.61 | KDM4E (0.36) | — | |
| SCHEMBL2017885 | 0.61 | — | — | |
| SCHEMBL8860815 | 0.60 | — | — | |
| SCHEMBL1083170 | 0.58 | — | — | |
| Methyl Alcohol SCHEMBL11203341 | 0.58 | — | — | |
| SCHEMBL6689397 | 0.58 | — | — | |
| SCHEMBL7857170 | 0.57 | NOS3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690229-A | Brand new synthesis of Montelukast Sodium and its preparation intermediates | SHANGHAI XIANGHUI MEDICAL TECHNOLOGY CO LTD | 2012-09-26 | — | — | CN | claimed |
| CN-118105513-A | Conjugates comprising self-degrading groups and methods related thereto | 乐高化学生物科学股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-11975076-B2 | Antibody-drug conjugates comprising branched linkers and methods related thereto | LEGOCHEM BIOSCIENCES, INC. (KR) | 2024-05-07 | — | — | US | disclosed |
| EP-3380124-B1 | CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO | LEGOCHEM BIOSCIENCES INC (KR) | 2024-04-03 | — | — | EP | disclosed |
| CN-117244076-A | Conjugates comprising self-degrading groups and methods related thereto | 乐高化学生物科学股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20220226496-A1 | LIGAND-DRUG CONJUGATE INCLUDING LINKER HAVING TRIS STRUCTURE | LEGOCHEM BIOSCIENCES, INC. (KR) | 2022-07-21 | — | — | US | disclosed |
| US-20220218840-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO | LIGACHEM BIOSCIENCES INC. (KR) | 2022-07-14 | — | — | US | disclosed |
| EP-3964236-A1 | LIGAND-DRUG CONJUGATE INCLUDING LINKER HAVING TRIS STRUCTURE | LegoChem Biosciences, Inc. (KR) | 2022-03-09 | — | — | EP | disclosed |
| CN-107847605-B | Antibody-drug conjugates comprising branched linkers and methods related thereto | 乐高化学生物科学股份有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-113727734-A | Ligand-drug conjugates comprising a linker having a tris structure | 乐高化学生物科学股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-20040010154-A1 | Diastereoselective hydrogenation of 1,3-hydroxyketones | SOLVIAS AG (CH) | 2004-01-15 | — | — | US | disclosed |
| EP-1378500-A1 | Diastereoselective hydrogenation of beta-hydroxy ketones | Solvias AG (CH) | 2004-01-07 | — | — | EP | disclosed |
| EP-1378501-A1 | Diastereoselective hydrogenation of beta-hydroxyketones | Solvias AG (CH) | 2004-01-07 | — | — | EP | disclosed |
| WO-2003044011-A1 | PYRROLE SYNTHESIS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-30 | — | — | WO | disclosed |
| WO-2003004450-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF STATIN DERIVATIVES ESPECIALLY 7-AMINO 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES, AND INTERMEDIATES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-01-16 | — | — | WO | disclosed |
| WO-2003004456-A1 | PROCESS FOR THE PREPARATION OF 7-AMINO SYN 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES VIA 6-CYANO SYN 3,5-DIHYDROXY HEXANOIC ACID DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-01-16 | — | — | WO | disclosed |
| WO-2003004455-A2 | PROCESS FOR THE PREPARATION OF 7-AMINO SYN 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES, INTERMEDIATES THEREOF AND METHODS FOR THEIR PREPARATION | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-01-16 | — | — | WO | disclosed |
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| CN-1274433-A | Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent | CLARIANT INT LTD (CH) | 2000-11-22 | — | — | CN | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |