SCHEMBL1268898

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1269276	0.99	MAPT (0.41)	PTGDR2PTGDRMAPTSMN1; SMN2POLB
	SCHEMBL1268503	0.94	PTGDR2 (0.41)	PTGDR2PTGDRMAPTSMN1; SMN2POLB
	SCHEMBL1269799	0.93	PTGDR2 (0.40)	PTGDR2PTGDRMAPTSMN1; SMN2POLB
	SCHEMBL1269539	0.93	KMT2A (0.43)	PTGDR2PTGDRMAPTSMN1; SMN2POLB
	SCHEMBL1268583	0.91	ALDH1A1 (0.39)	PTGDR2PTGDRMAPTSMN1; SMN2POLB
	SCHEMBL1268953	0.89	ALDH1A1 (0.45)	PTGDR2PTGDRMAPTSMN1; SMN2POLB
	SCHEMBL1268515	0.89	ALDH1A1 (0.41)	PTGDR2PTGDRMAPTPOLBALDH1A1
	SCHEMBL1269493	0.89	HTT (0.38)	PTGDR2PTGDRMAPTSMN1; SMN2ALDH1A1
	SCHEMBL1269786	0.88	PTGDR2 (0.46)	PTGDR2PTGDRMAPTSMN1; SMN2POLB
	SCHEMBL1269665	0.88	HTT (0.40)	MAPTSMN1; SMN2POLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.