SCHEMBL1268959

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1268887	0.90	ALDH1A1 (0.46)	ALDH1A1KDM4EMEN1KMT2ATDP1
	SCHEMBL1268585	0.86	ALDH1A1 (0.42)	ALDH1A1KDM4EMEN1KMT2ATDP1
	SCHEMBL5226632	0.85	CNR1 (0.43)	ALDH1A1KDM4EMEN1KMT2ALMNA
	SCHEMBL1269665	0.85	HTT (0.40)	ALDH1A1KDM4EMEN1KMT2ALMNA
	SCHEMBL1269568	0.85	ALDH1A1 (0.41)	ALDH1A1KDM4EMEN1KMT2ATDP1
	SCHEMBL1269493	0.84	HTT (0.38)	ALDH1A1KDM4EMEN1KMT2ATDP1
	SCHEMBL1269009	0.83	ALDH1A1 (0.39)	ALDH1A1KDM4EMEN1KMT2ATDP1
	SCHEMBL1269400	0.83	ALDH1A1 (0.47)	ALDH1A1KDM4EMEN1KMT2ATDP1
	SCHEMBL1269603	0.83	GAA (0.45)	ALDH1A1KDM4ELMNAHTTGAA
	SCHEMBL1269470	0.83	ALDH1A1 (0.40)	ALDH1A1KDM4EMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.