Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237291 | 0.78 | CYP17A1 (0.46) | CYP17A1CYP1A2IRAK4FFAR4DPP4 | |
| SCHEMBL11062025 | 0.77 | CYP17A1 (0.50) | CYP17A1CYP1A2IRAK4FFAR4DPP4 | |
| SCHEMBL6344984 | 0.74 | CYP17A1 (0.55) | CYP17A1CYP1A2DPP4RAB9AGSK3B | |
| SCHEMBL29833912 | 0.73 | IRAK4 (0.53) | CYP17A1CYP1A2IRAK4FFAR4RAB9A | |
| SCHEMBL12075537 | 0.70 | IRAK4 (0.57) | CYP17A1CYP1A2IRAK4FFAR4RAB9A | |
| SCHEMBL31020506 | 0.70 | IRAK4 (0.57) | CYP17A1CYP1A2IRAK4FFAR4RAB9A | |
| SCHEMBL15404558 | 0.70 | CYP17A1 (0.52) | CYP17A1CYP1A2IRAK4FFAR4RAB9A | |
| SCHEMBL6071403 | 0.70 | GSK3B (0.52) | CYP17A1CYP1A2DPP4RAB9AGSK3B | |
| SCHEMBL30716967 | 0.69 | CYP17A1 (0.64) | CYP17A1CYP1A2IRAK4FFAR4DPP4 | |
| SCHEMBL26970885 | 0.69 | CYP17A1 (0.64) | CYP17A1CYP1A2IRAK4FFAR4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028507-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028507-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | EGLN3, EGLN2, HIF1A | CYP17A1 308/4885CYP1A2 288/4885IRAK4 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.