Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perindoprilat SCHEMBL683210 | 1.00 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL22372411 | 1.00 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL28425122 | 1.00 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL564053 | 1.00 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL1269122 | 1.00 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL5598999 | 1.00 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL28425123 | 1.00 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL10590450 | 0.98 | ACE (0.77) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL682365 | 0.98 | ACE (0.77) | ACEMEN1KMT2AUSP2LMNA | |
| Hydrochloric Acid SCHEMBL10591200 | 0.97 | ACE (0.76) | ACEMEN1KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083644-A1 | BIOSENSING PLATFORM FOR DETECTING VIRAL INFECTIONS AND METHODS FOR SCREENING A MODULATOR OF VIRAL INFECTIONS AND PROTECTING THEREFROM | PD BIOMEDICAL CO., LTD. (CN) | 2022-04-28 | — | — | WO | disclosed |
| US-20220117936-A1 | BIOSENSING PLATFORM FOR DETECTING VIRAL INFECTIONS AND METHODS FOR SCREENING A MODULATOR OF VIRAL INFECTIONS AND PROTECTING THEREFROM | PIN JYE BIO TECH CO., LTD. (TW) | 2022-04-21 | — | — | US | disclosed |
| EP-2205639-B1 | ANTI-PCSK9 AND METHODS FOR TREATING LIPID AND CHOLESTEROL DISORDERS | MERCK SHARP & DOHME (US) | 2015-12-23 | — | — | EP | disclosed |
| US-20140161798-A1 | ANTI-PCSK9 AND METHODS FOR TREATING LIPID AND CHOLESTEROL DISORDERS | MERCK SHARP & DOHME CORP. (US) | 2014-06-12 | — | — | US | disclosed |
| US-8598320-B2 | Anti-PCSK9 and methods for treating lipid and cholesterol disorders | MERCK SHARP & DOHME CORP. (US) | 2013-12-03 | — | — | US | disclosed |
| US-8257921-B1 | NRIP1 regulation of apolipoprotein A1 | SCHERING CORPORATION (US) | 2012-09-04 | — | — | US | disclosed |
| WO-2012054438-A1 | ANTI-PCSK9 | SCHERING CORPORATION (US) | 2012-04-26 | — | — | WO | disclosed |
| US-20110033465-A1 | ANTI-PCSK9 AND METHODS FOR TREATING LIPID AND CHOLESTEROL DISORDERS | SCHERING CORPORATION (US) | 2011-02-10 | — | — | US | disclosed |
| EP-1635792-B1 | STABLE PHARMACEUTICAL COMPOSITIONS OF 2-AZA-BICYCLO¬3.3.0 -OCTANE-3-CARBOXYLIC ACID DERIVATIVES | TEVA PHARMA (IL) | 2009-03-04 | — | — | EP | disclosed |
| US-20080058404-A1 | Stable pharmaceutical compositions of 2-aza-bicyclo [3.3.0]-octane-3-carboxylic acid derivatives | TEVA PHARMACEUTICALS USA, INC. | 2008-03-06 | — | — | US | disclosed |
| US-20080015188-A1 | Stable pharmaceutical compositions of 2-aza-bicyclo(3.3.0)-octane-3-carboxylic acid derivatives | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-17 | — | — | US | disclosed |
| US-20080015188-A1 | Stable pharmaceutical compositions of 2-aza-bicyclo(3.3.0)-octane-3-carboxylic acid derivatives | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-17 | — | — | US | disclosed |
| US-20070212409-A1 | Stable pharmaceutical compositions for 2-aza-bicyclo [3.30]-octane-3-carboxylic acid derivatives | HRAKOVSHY JULIA | 2007-09-13 | — | — | US | disclosed |
| US-20070212409-A1 | Stable pharmaceutical compositions for 2-aza-bicyclo [3.30]-octane-3-carboxylic acid derivatives | HRAKOVSHY JULIA | 2007-09-13 | — | — | US | disclosed |
| EP-1385548-B1 | COMBINATIONS OF STEROL ABSORPTION INHIBITOR(S) WITH CARDIOVASCULAR AGENT(S) FOR THE TREATMENT OF VASCULAR CONDITIONS | SCHERING CORP (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-1541175-A2 | Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions | Schering Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005002548-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF 2-AZA-BICYCLO[3.3.0]-OCTANE-3-CARBOXYLIC ACID DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-01-13 | — | — | WO | disclosed |
| EP-1385548-A2 | COMBINATIONS OF STEROL ABSORPTION INHIBITOR(S) WITH CARDIOVASCULAR AGENT(S) FOR THE TREATMENT OF VASCULAR CONDITIONS | Schering Corporation (US) | 2004-02-04 | — | — | EP | disclosed |
| US-20030069221-A1 | Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions | SCHERING CORPORATION | 2003-04-10 | — | — | US | disclosed |
| WO-2002058731-A2 | COMBINATIONS OF STEROL ABSORPTION INHIBITOR(S) WITH CARDIOVASCULAR AGENT(S) FOR THE TREATMENT OF VASCULAR CONDITIONS | SCHERING CORPORATION (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110033465-A1 | ANTI-PCSK9 AND METHODS FOR TREATING LIPID AND CHOLESTEROL DISORDERS | PCSK9, PCSK7, CETP | ACE 126/4885MEN1 1119/4885KMT2A 1284/4885 |
| US-20080015188-A1 | Stable pharmaceutical compositions of 2-aza-bicyclo(3.3.0)-octane-3-carboxylic acid derivatives | AZI2, TET3, TET1 | ACE 955/4885MEN1 2486/4885KMT2A 449/4885 |
| US-20070212409-A1 | Stable pharmaceutical compositions for 2-aza-bicyclo [3.30]-octane-3-carboxylic acid derivatives | AZI2, CYP3A43, TPMT | ACE 2886/4885MEN1 3754/4885KMT2A 850/4885 |
| US-20080058404-A1 | Stable pharmaceutical compositions of 2-aza-bicyclo [3.3.0]-octane-3-carboxylic acid derivatives | AZI2, TPMT, CYP3A43 | ACE 2904/4885MEN1 3747/4885KMT2A 998/4885 |
| US-20030069221-A1 | Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions | CYP46A1, FABP2, SREBF1 | ACE 357/4885MEN1 1502/4885KMT2A 4682/4885 |
| US-20140161798-A1 | ANTI-PCSK9 AND METHODS FOR TREATING LIPID AND CHOLESTEROL DISORDERS | PCSK9, PCSK7, CETP | ACE 126/4885MEN1 1119/4885KMT2A 1284/4885 |
| US-20220117936-A1 | BIOSENSING PLATFORM FOR DETECTING VIRAL INFECTIONS AND METHODS FOR SCREENING A MODULATOR OF VIRAL INFECTIONS AND PROTECTING THEREFROM | ACE2, ACE, TMPRSS2 | ACE 2/4885MEN1 4392/4885KMT2A 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.