Perindoprilat

Perindoprilat

SCHEMBL683210

CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@H]2CCCC[C@@H]21)C(=O)O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 12/20 0.80
▸ MEN1 O00255 2/20 0.63
▸ KMT2A Q03164 2/20 0.63
▸ USP2 O75604 1/20 0.63
▸ LMNA P02545 1/20 0.63
▸ CYP3A4 P08684 1/20 0.61
▸ ALOX15 P16050 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perindoprilat SCHEMBL22372411 1.00 ACE (0.80) ACEMEN1KMT2AUSP2LMNA
Perindoprilat SCHEMBL28425122 1.00 ACE (0.80) ACEMEN1KMT2AUSP2LMNA
Perindoprilat SCHEMBL1269121 1.00 ACE (0.80) ACEMEN1KMT2AUSP2LMNA
Perindoprilat SCHEMBL564053 1.00 ACE (0.80) ACEMEN1KMT2AUSP2LMNA
Perindoprilat SCHEMBL1269122 1.00 ACE (0.80) ACEMEN1KMT2AUSP2LMNA
Perindoprilat SCHEMBL5598999 1.00 ACE (0.80) ACEMEN1KMT2AUSP2LMNA
Perindoprilat SCHEMBL28425123 1.00 ACE (0.80) ACEMEN1KMT2AUSP2LMNA
SCHEMBL10590450 0.98 ACE (0.77) ACEMEN1KMT2AUSP2LMNA
SCHEMBL682365 0.98 ACE (0.77) ACEMEN1KMT2AUSP2LMNA
Hydrochloric Acid SCHEMBL10591200 0.97 ACE (0.76) ACEMEN1KMT2AUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN BRAINCELLS INC. (US) 2011-11-03 — — US disclosed
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN BRAINCELLS INC. (US) 2011-11-03 — — US disclosed
US-20110046090-A1 MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS BRAINCELLS INC. (US) 2011-02-24 — — US disclosed
US-20110046090-A1 MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS BRAINCELLS INC. (US) 2011-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046090-A1 MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS GAP43, GABRB1, GABRB3 ACE 4514/4885MEN1 3647/4885KMT2A 2044/4885
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN NGF, DCX, BDNF ACE 6/4885MEN1 1910/4885KMT2A 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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