Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269375 | 0.86 | KMT2A (0.47) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1269229 | 0.82 | MAPK1 (0.50) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1268171 | 0.77 | POLB (0.48) | ALOX15SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL1268378 | 0.76 | NPC1 (0.47) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16441364 | 0.76 | KMT2A (0.45) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1269270 | 0.76 | EGLN1 (0.51) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1269302 | 0.76 | KMT2A (0.47) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1268419 | 0.76 | KMT2A (0.47) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1269238 | 0.75 | RAB9A (0.45) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1269310 | 0.75 | RAB9A (0.45) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | GSK3B, GSK3A, GSKIP | ALOX15 4220/4885SMN1; SMN2 865/4885GAA 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.