Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268378 | 0.91 | NPC1 (0.47) | HTR6ALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL1269211 | 0.90 | MAPK1 (0.47) | MAPK1HTR6ALDH1A1HTTMEN1 | |
| SCHEMBL1268273 | 0.87 | HTR6 (0.42) | MAPK1HTR6ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL12898308 | 0.87 | HTR6 (0.44) | MAPK1HTR6ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL12898310 | 0.87 | HTR6 (0.44) | MAPK1HTR6ALDH1A1HTTMEN1 | |
| SCHEMBL12898208 | 0.86 | KDM4E (0.42) | CNR1MAPK1HTR6ALDH1A1SMN1; SMN2 | |
| SCHEMBL12898206 | 0.86 | MAPK1 (0.42) | MAPK1HTR6ALDH1A1HTTLMNA | |
| SCHEMBL1268202 | 0.85 | HTR6 (0.42) | MAPK1HTR6ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1268340 | 0.84 | KMT2A (0.46) | SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL1268088 | 0.84 | MAPK1 (0.46) | MAPK1HTR6HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | GSK3B, GSK3A, GSKIP | CNR1 4569/4885MAPK1 276/4885HTR6 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.