SCHEMBL126928

SCHEMBL126928

CC(=O)N1c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.55
MAPT P10636 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
SNCA P37840 1/20 0.46
P2RX4 Q99571 8/20 0.42
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
BRCA1 P38398 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NOX1 Q9Y5S8 1/20 0.38
MYC P01106 1/20 0.38
PTPN1 P18031 1/20 0.38
P2RX1 P51575 1/20 0.37
HSD17B3 P37058 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377171 1.00 SMN1; SMN2 (0.55) SMN1; SMN2MAPTNPSR1SNCAP2RX4
SCHEMBL29354599 1.00 SMN1; SMN2 (0.55) SMN1; SMN2MAPTNPSR1SNCAP2RX4
SCHEMBL23552916 0.92 SMN1; SMN2 (0.49) SMN1; SMN2MAPTNPSR1SNCAP2RX4
SCHEMBL25137196 0.88 MAPT (0.46) SMN1; SMN2MAPTNPSR1SNCAP2RX4
Fenuron SCHEMBL3668613 0.80 MAPT (0.45) SMN1; SMN2MAPTNPSR1P2RX4FTO
SCHEMBL12714459 0.80 MAPT (0.42) SMN1; SMN2MAPTNPSR1SNCAP2RX4
SCHEMBL10600768 0.80 MAPT (0.54) SMN1; SMN2MAPTNPSR1P2RX4GAA
SCHEMBL12311055 0.80 MAPT (0.54) SMN1; SMN2MAPTNPSR1P2RX4KDM4E
SCHEMBL6037027 0.78 MAPT (0.49) SMN1; SMN2MAPTNPSR1GAAKDM4E
SCHEMBL27345794 0.77 SMN1; SMN2 (0.51) SMN1; SMN2MAPTNPSR1P2RX4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2011 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12625139-B2 Methods for modulation of acetyltransferase activity and applications thereof including treatments THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2026-05-12 US claimed
US-12540314-B2 Peroxidase activity towards 10-acetyl-3,7-dihydroxyphenoxazine CODEXIS, INC. (US) 2026-02-03 US claimed
US-12275782-B2 Means and methods for the determination of the biological activity of neurotoxin polypeptides in cells MERZ PHARMA GMBH & CO. KGAA (DE) 2025-04-15 US claimed
US-20240345078-A1 ULTRASENSITIVE RAPID ANTIGEN DETECTION KIT AND DETECTION METHOD THEREOF THE UNIVERSITY OF HONG KONG (HK) 2024-10-17 US claimed
US-20240301367-A1 PEROXIDASE ACTIVITY TOWARDS 10-ACETYL-3,7-DIHYDROXYPHENOXAZINE CODEXIS, INC. (US) 2024-09-12 US claimed
WO-2024177860-A1 IN CHEMICO TEST FOR TOXICITY LEBRUN LABS LLC (US) 2024-08-29 WO claimed
US-20240270833-A1 Means and Methods for the Determination of the Biological Activity of Neurotoxin Polypeptides in Cells MERZ PHARMA GMBH & CO. KGAA (DE) 2024-08-15 US claimed
US-12012620-B2 Peroxidase activity towards 10-acetyl-3,7-dihydroxyphenoxazine CODEXIS, INC. (US) 2024-06-18 US claimed
US-11976110-B2 Means and methods for the determination of the biological activity of neurotoxin polypeptides in cells MERZ PHARMA GMBH & CO. KGAA (DE) 2024-05-07 US claimed
WO-2024031149-A1 METHODS FOR THE DETECTION OF MYELOPEROXIDASE THE UNIVERSITY OF SYDNEY (AU) 2024-02-15 WO claimed
WO-2007091033-A1 PORTABLE KIT AND METHOD FOR THE ESTIMATION OF TIME OF DEATH OF A CORPSE BY DETERMINING THE HYPOXANTHINE CONCENTRATION IN THAT CORPSE DEPENDENT ON TEMPERATURE AND TIME UNIVERSITETET I OSLO (NO) 2007-08-16 WO claimed
US-20070136840-A1 GRG23 and GRG 51 genes conferring herbicide resistance ATHENIX CORPORATION (US) 2007-06-14 US claimed
US-20070111316-A1 Detection of lysophosphatidylcholine for prognosis or diagnosis of a systemic inflammatory condition BECTON, DICKINSON AND COMPANY 2007-05-17 US claimed
WO-2007038758-A2 DETECTION OF LYSOPHOSPHATIDYLCHOLINE FOR PROGNOSIS OR DIAGNOSIS OF A SYSTEMIC INFLAMMATORY CONDITION BECTON, DICKINSON AND COMPANY (US) 2007-04-05 WO claimed
EP-1293562-B1 Fungal glyoxal oxidases BAYER CROPSCIENCE AG (DE) 2006-11-22 EP claimed
US-20050118152-A1 Analytical method for detecting alkaline sphingomyelinase and kit for use in such method VSL PHARMACEUTICALS, INC. 2005-06-02 US claimed
CN-1608138-A Analytical method for detecting alkaline sphingomyelinase and kit for use in the method ACTIAL FARMACEUTICA LDA (PT) 2005-04-20 CN claimed
EP-1456405-A2 METHOD AND KIT FOR DETECTING ALKALINE SPHINGOMYELINASE ACTIAL Farmaceutica Lda. (PT) 2004-09-15 EP claimed
WO-2003056031-A2 METHOD AND KIT FOR DETECTING ALKALINE SPHINGOMYELINASE ACTIAL FARMACÊUTICA, LDA. (PT) 2003-07-10 WO claimed
WO-1999001768-A1 PEROXIDASE-CATALYSED FLUORESCENCE NYCOMED AMERSHAM PLC (GB) 1999-01-14 WO claimed