SCHEMBL6037027

SCHEMBL6037027

CCCCCCCCCCCCc1cc2c(cc1O)Oc1cc(O)ccc1N2C(C)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
TYR P14679 2/20 0.49
CYP3A4 P08684 2/20 0.49
HTT P42858 2/20 0.49
ALOX15 P16050 2/20 0.49
TP53 P04637 1/20 0.49
ALOX5 P09917 1/20 0.49
TSHR P16473 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
NPSR1 Q6W5P4 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 3/20 0.39
GLA P06280 3/20 0.39
GAA P10253 3/20 0.39
HPGD P15428 3/20 0.39
USP2 O75604 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377171 0.78 SMN1; SMN2 (0.55) MAPTCYP3A4NPSR1SMN1; SMN2KDM4E
SCHEMBL29354599 0.78 SMN1; SMN2 (0.55) MAPTCYP3A4NPSR1SMN1; SMN2KDM4E
SCHEMBL126928 0.78 SMN1; SMN2 (0.55) MAPTCYP3A4NPSR1SMN1; SMN2KDM4E
SCHEMBL23963766 0.75 HTT (0.44) MAPTMEN1KMT2ATYRCYP3A4
SCHEMBL8867287 0.72 TYR (0.55) MAPTMEN1KMT2ATYRCYP3A4
SCHEMBL23552916 0.72 SMN1; SMN2 (0.49) MAPTMEN1KMT2ANPSR1SMN1; SMN2
Ethylene SCHEMBL28261437 0.71 ALOX5 (0.69) MAPTMEN1KMT2ATYRCYP3A4
SCHEMBL8370545 0.71 ALOX5 (0.73) MAPTMEN1KMT2ATYRCYP3A4
SCHEMBL7036605 0.71 ALOX5 (0.73) MAPTMEN1KMT2ATYRCYP3A4
SCHEMBL126053 0.71 ALOX5 (0.73) MAPTMEN1KMT2ATYRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20060025335-A1 Netrin compositions and methods of using the same NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2006-02-02 US disclosed
WO-2005074556-A2 NETRIN COMPOSITIONS AND METHODS OF USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2005-08-18 WO disclosed