Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | PPARA | Q07869 | 3/20 | 0.71 |
| ▸ | PPARG | P37231 | 1/20 | 0.71 |
| ▸ | PPARD | Q03181 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18729782 | 0.87 | ALDH1A1 (0.69) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| SCHEMBL17318086 | 0.87 | ALDH1A1 (0.69) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Fluoride SCHEMBL25252504 | 0.85 | ALDH1A1 (0.67) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| SCHEMBL29970179 | 0.84 | ALDH1A1 (0.65) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| SCHEMBL25297944 | 0.84 | ALDH1A1 (0.65) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL1869396 | 0.84 | ALDH1A1 (1.00) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL113794 | 0.84 | ALDH1A1 (1.00) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL29376951 | 0.84 | ALDH1A1 (1.00) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| SCHEMBL28408730 | 0.83 | ALDH1A1 (0.63) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL5564539 | 0.82 | ALDH1A1 (0.96) | ALDH1A1PPARAPPARGPPARDPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879907-B2 | Peroxisome Proliferator-Activated Receptor (PPAR) activators such as 3-{4-[3-(4-benzyloxy-3-methoxyphenyl)propyl]-3-butoxyphenyl}propanoic acid, used in dermatology, cosmetics, cardiovascular diseases, immunology and/or lipid metabolism | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-02-01 | — | — | US | disclosed |
| US-20100158843-A1 | NOVEL 3-PHENYLPROPANOIC COMPOUND ACTIVATORS OF RECEPTORS OF PPAR TYPE AND PHARMACEUTICAL/COSMETIC COMPOSITIONS COMPRISED THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158843-A1 | NOVEL 3-PHENYLPROPANOIC COMPOUND ACTIVATORS OF RECEPTORS OF PPAR TYPE AND PHARMACEUTICAL/COSMETIC COMPOSITIONS COMPRISED THEREOF | PPARG, PPARA, PPARD | ALDH1A1 423/4885PPARA 2/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.