SCHEMBL126934

SCHEMBL126934

[CH2]OCCF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759193 0.79
SCHEMBL353834 0.77
SCHEMBL7857356 0.74
SCHEMBL5456662 0.72
SCHEMBL6863806 0.72
SCHEMBL9118156 0.72
SCHEMBL4512521 0.71
SCHEMBL355018 0.67
SCHEMBL158305 0.67
SCHEMBL935320 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348384-A1 Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides UCB PHARMA GMBH (DE) 2023-11-02 US claimed
CN-110121499-B (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides 优时比制药有限公司 2022-12-20 CN claimed
US-11345662-B2 Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides UCB PHARMA GMBH (DE) 2022-05-31 US claimed
US-20220048858-A1 Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides UCB PHARMA GMBH (DE) 2022-02-17 US claimed
CN-113993845-A N- (phenyl) -indole-3-sulfonamide derivatives and related compounds as GPR17 modulators for the treatment of CNS disorders, such as multiple sclerosis 优时比制药有限公司 2022-01-28 CN claimed
WO-2020030107-A1 PHARMACEUTICAL COMPOSITION CONTAINING AMIDE DERIVATIVES, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 江苏豪森药业集团有限公司 2020-02-13 WO claimed
US-9051331-B2 Substituted dihydro benzocycloalkyloxymethyl oxazolopyrimidinones, preparation and use thereof SANOFI (FR) 2015-06-09 US claimed
US-8703807-B2 Azaspirodecanone compounds HOFFMANN-LA ROCHE INC. (US) 2014-04-22 US claimed
EP-2686300-A1 NEW AZASPIRODECANONE COMPOUNDS F.HOFFMANN-LA ROCHE AG (CH) 2014-01-22 EP claimed
EP-2672974-A1 HYBRID OPIOID COMPOUNDS AND COMPOSITIONS Qrxpharma Limited (AU) 2013-12-18 EP claimed
EP-2194046-A1 Triazolone derivative Eisai R&D Management Co., Ltd. (JP) 2010-06-09 EP claimed
US-20090270433-A1 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-10-29 US claimed
US-20090036453-A1 Pyrrolopyridazinone Compound UBE INDUSTRIES, LTD. (JP) 2009-02-05 US claimed
EP-2000465-A1 TRIAZOLONE DERIVATIVE Eisai R&D Management Co., Ltd. (JP) 2008-12-10 EP claimed
EP-1982986-A1 PYRROLOPYRIDAZINONE COMPOUND Ube Industries, Ltd. (JP) 2008-10-22 EP claimed
US-20080015199-A1 Triazolone derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-01-17 US claimed
US-4960884-A Insecticides, nematocides, pesticides and miticides FMC CORPORATION (US) 1990-10-02 US claimed
EP-0063905-B1 FUNGICIDAL N-PHENYLCARBAMATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-08-14 EP claimed
US-4482546-A Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-13 US claimed
EP-0063905-A1 Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-03 EP claimed