Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315854 | 0.89 | OPRM1 (0.43) | OPRM1OPRL1CCR1 | |
| SCHEMBL3315844 | 0.89 | OPRM1 (0.43) | OPRM1OPRL1CCR1 | |
| SCHEMBL12694729 | 0.88 | BDKRB1 (0.41) | OPRM1OPRL1 | |
| SCHEMBL5125509 | 0.83 | ATM (0.37) | RAB9ALMNAMEN1MAPTKMT2A | |
| SCHEMBL3318811 | 0.81 | OPRM1 (0.38) | OPRM1OPRL1 | |
| SCHEMBL12694732 | 0.80 | HSD17B10 (0.35) | RAB9AMEN1KMT2ACCR1 | |
| SCHEMBL3311065 | 0.78 | OPRM1 (0.41) | OPRM1OPRL1RAB9A | |
| SCHEMBL3310795 | 0.77 | OPRM1 (0.40) | OPRM1OPRL1RAB9A | |
| SCHEMBL3316346 | 0.76 | BDKRB1 (0.40) | OPRM1OPRL1 | |
| SCHEMBL3316351 | 0.76 | BDKRB1 (0.40) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278319-B2 | Substituted spiroamine compounds | GRUENENTHAL GMBH (DE) | 2012-10-02 | — | — | US | claimed |