Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL3668356 | 0.97 | CA1 (0.75) | CA1CA2POLBKMT2AALDH1A1 | |
| SCHEMBL391423 | 0.86 | — | — | |
| SCHEMBL2723676 | 0.86 | — | — | |
| SCHEMBL2017488 | 0.83 | CA1 (1.00) | CA1CA2POLBKMT2AALDH1A1 | |
| SCHEMBL21356989 | 0.83 | CA1 (1.00) | CA1CA2POLBKMT2AALDH1A1 | |
| SCHEMBL392889 | 0.83 | CA1 (1.00) | CA1CA2POLBKMT2AALDH1A1 | |
| SCHEMBL2724764 | 0.83 | CA1 (1.00) | CA1CA2POLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29819829 | 0.83 | CA1 (0.88) | CA1CA2POLBKMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29021660 | 0.81 | CA1 (0.58) | CA1CA2POLBKMT2AALDH1A1 | |
| SCHEMBL28174597 | 0.80 | CA1 (0.94) | CA1CA2POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120171222-A1 | METHODS AND COMPOSITIONS INVOLVING NUCLEOTIDE REPEAT DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-07-05 | — | — | US | claimed |
| WO-2007121272-A2 | METHODS AND COMPOSITIONS INVOLVING NUCLEOTIDE REPEAT DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-10-25 | — | — | WO | claimed |
| US-8771965-B2 | Methods and compositions involving nucleotide repeat disorders | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120171222-A1 | METHODS AND COMPOSITIONS INVOLVING NUCLEOTIDE REPEAT DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-07-05 | — | — | US | disclosed |
| US-8158364-B2 | Methods and compositions involving nucleotide repeat disorders | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110033480-A1 | METHODS AND COMPOSITIONS INVOLVING NUCLEOTIDE REPEAT DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2011-02-10 | — | — | US | disclosed |
| WO-2007121272-A2 | METHODS AND COMPOSITIONS INVOLVING NUCLEOTIDE REPEAT DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-10-25 | — | — | WO | disclosed |