Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.75 |
| ▸ | CA2 | P00918 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL1269504 | 0.97 | CA1 (0.70) | CA1CA2POLBKMT2ATSHR | |
| SCHEMBL21356989 | 0.87 | CA1 (1.00) | CA1CA2POLBKMT2ATSHR | |
| SCHEMBL2724764 | 0.87 | CA1 (1.00) | CA1CA2POLBKMT2ATSHR | |
| SCHEMBL392889 | 0.87 | CA1 (1.00) | CA1CA2POLBKMT2ATSHR | |
| SCHEMBL2017488 | 0.87 | CA1 (1.00) | CA1CA2POLBKMT2ATSHR | |
| SCHEMBL28174597 | 0.84 | CA1 (0.94) | CA1CA2POLBKMT2ATSHR | |
| SCHEMBL391423 | 0.84 | — | — | |
| SCHEMBL2723676 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL29819829 | 0.81 | CA1 (0.88) | CA1CA2POLBKMT2ATSHR | |
| Trifluoroacetic Acid SCHEMBL29021660 | 0.79 | CA1 (0.58) | CA1CA2POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155678-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC Neurosciences GmbH (DE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008125570-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2008-10-23 | — | — | WO | disclosed |