Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | PDE4A | P27815 | 8/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12562573 | 0.81 | ALDH2 (0.46) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28169080 | 0.81 | ALDH2 (0.46) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21053510 | 0.81 | PDE4A (0.49) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18640884 | 0.81 | PDE4A (0.49) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19996026 | 0.81 | PDE4A (0.49) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10200945 | 0.81 | TSHR (0.57) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22831445 | 0.81 | TSHR (0.57) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18590504 | 0.81 | TSHR (0.61) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20475320 | 0.81 | TSHR (0.57) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL560686 | 0.81 | TSHR (0.57) | TSHRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099451-A1 | NEW COMPOUNDS AND METHODS | Transition Bio Limited (GB) | 2025-05-15 | — | — | WO | disclosed |
| US-11518754-B2 | Radiolabeled pharmaceuticals and methods of making and using same | YALE UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
| US-11518754-B2 | Radiolabeled pharmaceuticals and methods of making and using same | YALE UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
| WO-2018152339-A1 | RADIOLABELED PHARMACEUTICALS AND METHODS OF MAKING AND USING SAME | YALE UNIVERSITY (US) | 2018-08-23 | — | — | WO | disclosed |
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
| US-4699918-A | ANTICOAGULANTS, ANTIARRHYTHMIA AGENTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1987-10-13 | — | — | US | disclosed |
| US-4556674-A | ANTICOAGULANTS, ANTIARRHYTHMIA AGENTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1985-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | GSK3B, GSK3A, GSKIP | TSHR 4679/4885PDE4A 639/4885PDE4B 686/4885 |
| US-11518754-B2 | Radiolabeled pharmaceuticals and methods of making and using same | SLC18A2, SLC18A3, SLC1A2 | TSHR 1884/4885PDE4A 1033/4885PDE4B 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.