Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | PDE2A | O00408 | 7/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660660 | 1.00 | HDAC1 (0.41) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL1988533 | 0.91 | HDAC1 (0.53) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL12697480 | 0.91 | HDAC1 (0.53) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL12604735 | 0.91 | HDAC1 (0.41) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL12697450 | 0.90 | ADRB2 (0.41) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL1987151 | 0.90 | ADRB2 (0.41) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL12697556 | 0.89 | HDAC1 (0.39) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL1986867 | 0.89 | HDAC1 (0.39) | HDAC1HDAC8HDAC6PDE2ACSNK1D | |
| SCHEMBL12604749 | 0.89 | HDAC1 (0.53) | HDAC1HDAC8HDAC6PDE2AKDM4E | |
| SCHEMBL1988501 | 0.89 | HDAC1 (0.53) | HDAC1HDAC8HDAC6PDE2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307394-B1 | SULPHONAMIDES AS VANILLOID RECEPTOR ANTAGONIST | AMOREPACIFIC CORP (KR) | 2012-09-26 | — | — | EP | disclosed |
| WO-2010002209-A2 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2010-01-07 | — | — | WO | disclosed |