Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 5/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547168 | 0.84 | ALOX5 (0.40) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL13052388 | 0.82 | ALOX5 (0.47) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL12418974 | 0.81 | ALOX5 (0.40) | ALOX5PRKDCPIK3CDPIK3CBCDC25A | |
| SCHEMBL12419234 | 0.81 | ALOX5 (0.41) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL15164538 | 0.81 | ALOX5 (0.58) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL24443021 | 0.80 | PRKDC (0.36) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL20615293 | 0.80 | PRKDC (0.36) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL13050915 | 0.79 | ALOX5 (0.44) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL22622635 | 0.78 | ALOX5 (0.41) | ALOX5PRKDCPIK3CDPIK3CBATM | |
| SCHEMBL22622655 | 0.78 | ALOX5 (0.41) | ALOX5PRKDCPIK3CDPIK3CBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012048781-A1 | TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-04-19 | — | — | WO | disclosed |