SCHEMBL1269946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1269951	0.91	PTGDR2 (0.41)	PTGDR2PTGDRALDH1A1HSD11B1PIK3C3
	SCHEMBL1269586	0.90	PIK3C3 (0.38)	PTGDR2PTGDRALDH1A1MAPTHSD11B1
	SCHEMBL1269518	0.89	PTGDR (0.39)	PTGDR2PTGDRALDH1A1MAPTHSD11B1
	SCHEMBL1269948	0.88	PTGDR (0.38)	PTGDR2PTGDRHSD11B1PIK3C3FLT1
	SCHEMBL1269748	0.87	PTGDR2 (0.43)	PTGDR2PTGDRALDH1A1NPC1MAPT
	SCHEMBL1268967	0.86	PTGDR (0.36)	PTGDR2PTGDRHSD11B1PIK3C3FLT1
	SCHEMBL1269493	0.85	HTT (0.38)	PTGDR2PTGDRALDH1A1MAPTLMNA
	SCHEMBL1269665	0.85	HTT (0.40)	ALDH1A1NPC1MAPTLMNAPOLB
	SCHEMBL1268682	0.83	KMT2A (0.43)	ALDH1A1NPC1MAPTLMNAPOLB
	SCHEMBL1268610	0.79	SMN1; SMN2 (0.37)	PTGDR2PTGDRALDH1A1MAPTPIK3C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.