SCHEMBL1269748

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1268565	0.92	PTGDR2 (0.43)	PTGDR2PTGDRALDH1A1NPC1MAPT
	SCHEMBL1269048	0.90	PIK3C3 (0.39)	PTGDR2PTGDRALDH1A1MAPTPPARG
	SCHEMBL1268561	0.89	PTGDR2 (0.42)	PTGDR2PTGDRALDH1A1PPARGPPARA
	SCHEMBL1269929	0.88	PTGDR2 (0.42)	PTGDR2PTGDRALDH1A1MAPTPPARG
	SCHEMBL1268503	0.87	PTGDR2 (0.41)	PTGDR2PTGDRALDH1A1MAPTMEN1
	SCHEMBL1269946	0.87	PTGDR2 (0.40)	PTGDR2PTGDRALDH1A1NPC1MAPT
	SCHEMBL1269589	0.86	PTGDR2 (0.40)	PTGDR2PTGDRALDH1A1PPARGPPARA
	SCHEMBL1269799	0.86	PTGDR2 (0.40)	PTGDR2PTGDRALDH1A1MAPTMEN1
	SCHEMBL1269706	0.85	ALDH1A1 (0.42)	PTGDR2PTGDRALDH1A1NPC1MAPT
	SCHEMBL1268791	0.81	PTGDR2 (0.41)	PTGDR2PTGDRALDH1A1MAPTPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.