SCHEMBL12701957

SCHEMBL12701957

C=C(C)C(=O)OCCCCCCCCCCC[SiH](C)C

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.65
POLB P06746 1/20 0.53
APEX1 P27695 1/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
THRB P10828 1/20 0.47
ALDH1A1 P00352 4/20 0.37
CYP3A4 P08684 1/20 0.35
NAAA Q02083 1/20 0.33
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EPHX1 P07099 1/20 0.32
ACHE P22303 6/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1455777 0.98 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2307199 0.92 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
Fluoride SCHEMBL28074750 0.91 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5607699 0.86 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554406 0.86 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554429 0.86 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22023212 0.86 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554423 0.86 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554404 0.86 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3502350 0.86 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9018332-B2 Polyorganosiloxane containing methacryloxy group or acryloxy group and method for producing the same DOW CORNING TORAY COMPANY, LTD. (JP) 2015-04-28 US disclosed
US-20110092660-A1 Polyorganosiloxane Containing Methacryloxy Group Or Acryloxy Group And Method For Producing The Same DOW CORNING TORAY COMPANY, LTD. (JP) 2011-04-21 US disclosed