SCHEMBL2307199

SCHEMBL2307199

C=C(C)C(=O)OCCC[SiH](C)C

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.58
THRB P10828 1/20 0.50
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 4/20 0.39
HPGD P15428 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28074750 0.98 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1455777 0.94 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12701957 0.92 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16750970 0.89 THRB (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4448962 0.86 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6924051 0.86 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2468776 0.86 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9847146 0.85 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8470085 0.85 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19399230 0.84 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102762655-B Surface-modified hydrogels and hydrogel microparticles DOW CORNING CORP. (US) 2016-05-11 CN claimed
CN-102666665-B Silicone compositions comprising a swollen silicone gel DOW CORNING 2015-07-22 CN claimed
CN-102762655-A Surface-modified hydrogels and hydrogel microparticles DOW CORNING 2012-10-31 CN claimed
CN-102666665-A Silicone compositions comprising a swollen silicone gel DOW CORNING 2012-09-12 CN claimed
CN-101501088-B Silicone acrylate hybrid compositions DOW CORNING CORP. (US) 2011-11-30 CN claimed
CN-101501088-A Silicone acrylate hybrid compositions DOW CORNING (US) 2009-08-05 CN claimed
EP-1139921-B1 LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INST OF TECHN (US) 2007-03-07 EP claimed
JP-2004500585-A 2004-01-08 JP claimed
US-20030173691-A1 Lenses capable of post-fabrication power modification DEPARTMENT OF VETERANS AFFAIRS 2003-09-18 US claimed
CN-1440551-A Phase contrast variation of photo-induced refractive material CALIFORNIA INST OF TECHN (US) 2003-09-03 CN claimed
US-20030093150-A1 Lanses capable of post-fabrication power modification DEPARTMENT OF VETERANS AFFAIRS 2003-05-15 US claimed
US-20030090624-A1 Lenses capable of post-fabrication power modification REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2003-05-15 US claimed
US-20030090013-A1 Lenses capable of post-fabrication power modification REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2003-05-15 US claimed
EP-1281176-A2 PHASE CONTRAST VARIATION OF A PHOTO-INDUCED REFRACTIVE MATERIAL California Institute Of Technology (US) 2003-02-05 EP claimed
US-6450642-B1 Lenses capable of post-fabrication power modification CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-09-17 US claimed
US-20020042004-A1 Phase contrast variation of a photo-induced refractive material CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-04-11 US claimed
WO-2001086647-A2 PHASE CONTRAST VARIATION OF A PHOTO-INDUCED REFRACTIVE MATERIAL CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2001-11-15 WO claimed
EP-1139921-A1 LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2001-10-10 EP claimed
WO-2000041650-A1 LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-07-20 WO claimed
EP-3192823-B1 METHOD FOR FORMING AN ASPHERIC INTRAOCULAR LENS RXSIGHT INC (US) 2025-09-10 EP disclosed
CN-111465392-B Transdermal therapeutic system for transdermal administration of guanfacine comprising a silicone polymer 罗曼治疗系统股份公司 2024-12-17 CN disclosed
EP-2756026-B1 USING THE LIGHT ADJUSTABLE LENS (LAL) TO INCREASE THE DEPTH OF FOCUS BY INDUCING TARGETED AMOUNTS OF ASPHERICITY RXSIGHT INC (US) 2024-12-11 EP disclosed
CN-118406451-A Water-based adhesive and preparation method and application thereof 齐河力厚化工有限公司 2024-07-30 CN disclosed
US-20240228800-A1 COATING MATERIAL, COATING LAYER, AND LIGHT-EMITTING DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-07-11 US disclosed
US-20230170450-A1 COMPOSITE MATERIAL, FILM, AND LIGHT-EMITTING DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-01 US disclosed
CN-114599349-A Transdermal therapeutic system for transdermal administration of fingolimod 罗曼治疗系统股份公司 2022-06-07 CN disclosed
CN-114025748-A Transdermal therapeutic system comprising an active agent-containing layer comprising a silicone-containing polymer and a skin contact layer comprising a silicone gel adhesive 罗曼治疗系统股份公司 2022-02-08 CN disclosed
US-20220015893-A1 METHOD OF ADJUSTING A BLENDED EXTENDED DEPTH OF FOCUS LIGHT ADJUSTABLE LENS WITH LATERALLY OFFSET AXES RXSIGHT, INC. 2022-01-20 US disclosed
US-11191637-B2 Blended extended depth of focus light adjustable lens with laterally offset axes RXSIGHT, INC. (US) 2021-12-07 US disclosed
US-11135052-B2 Method of adjusting a blended extended depth of focus light adjustable lens with laterally offset axes RXSIGHT, INC. 2021-10-05 US disclosed
US-10874505-B2 Using the light adjustable lens (LAL) to increase the depth of focus by inducing targeted amounts of asphericity RXSIGHT, INC. (US) 2020-12-29 US disclosed
CN-112080184-A Anti-whitening primer and preparation method thereof 英济股份有限公司 2020-12-15 CN disclosed
CN-112040936-A Transdermal therapeutic system for the transdermal administration of solifenacin 罗曼治疗系统股份公司 2020-12-04 CN disclosed
CN-111971032-A Transdermal therapeutic system comprising silicone acrylic hybrid polymers 罗曼治疗系统股份公司 2020-11-20 CN disclosed
CN-111971033-A Transdermal therapeutic system comprising silicone acrylic hybrid polymers 罗曼治疗系统股份公司 2020-11-20 CN disclosed
CN-111867569-A Transdermal therapeutic system comprising silicone acrylic hybrid polymers 罗曼治疗系统股份公司 2020-10-30 CN disclosed
CN-111867570-A Transdermal therapeutic system comprising nicotine and silicone acrylic hybrid polymers 罗曼治疗系统股份公司 2020-10-30 CN disclosed
CN-111787913-A Transdermal therapeutic system for transdermal administration of buprenorphine comprising silicone acrylic hybrid polymers 罗曼治疗系统股份公司 2020-10-16 CN disclosed
CN-111491621-A Transdermal therapeutic system for transdermal administration of guanfacine containing silicone acrylic hybrid polymers 罗曼治疗系统股份公司 2020-08-04 CN disclosed
CN-111447926-A Transdermal therapeutic system for the transdermal administration of guanfacine comprising at least one additive 罗曼治疗系统股份公司 2020-07-24 CN disclosed
CN-111093639-A Transdermal therapeutic system for transdermal administration of rivastigmine 罗曼治疗系统股份公司 2020-05-01 CN disclosed
CN-110809466-A Transdermal therapeutic system containing hybrid polymer of scopolamine and siloxane acrylic acid 罗曼治疗系统股份公司 2020-02-18 CN disclosed
CN-110799180-A Transdermal therapeutic system containing asenapine and siloxane acrylic hybrid polymer 罗曼治疗系统股份公司 2020-02-14 CN disclosed
US-10470874-B2 Adjustable optical elements with enhanced ultraviolet protection RXSIGHT, INC. (US) 2019-11-12 US disclosed
US-20190262125-A9 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION RXSIGHT, INC. (US) 2019-08-29 US disclosed
CN-109791376-A The manufacturing method of the resist pattern coating composition of solvent displacement is used 日产化学株式会社 2019-05-21 CN disclosed
US-20190142576-A1 METHOD OF ADJUSTING A BLENDED EXTENDED DEPTH OF FOCUS LIGHT ADJUSTABLE LENS WITH LATERALLY OFFSET AXES RXSIGHT, INC. (US) 2019-05-16 US disclosed
US-20190133755-A1 BLENDED EXTENDED DEPTH OF FOCUS LIGHT ADJUSTABLE LENS WITH LATERALLY OFFSET AXES RXSIGHT, INC. (US) 2019-05-09 US disclosed
US-10040947-B2 Primer composition MITSUI CHEMICALS, INC. (JP) 2018-08-07 US disclosed
US-10010406-B2 Using the light adjustable lens (LAL) to increase the depth of focus by inducing targeted amounts of asphericity RXSIGHT, INC. (US) 2018-07-03 US disclosed
US-9883940-B2 Multilens intraocular system implantation with injectable accommodation material RXSIGHT, INC. (US) 2018-02-06 US disclosed
CN-107406554-A Multiphase acid-organosilicon crylic acid class mixes viscoelastic composition and preparation method thereof 美国道康宁公司 2017-11-28 CN disclosed
US-20170307779-A1 Silicone Elastomer-Silicone Hydrogel Hybrid Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2017-10-26 US disclosed
US-20170307778-A1 Silicone Elastomer-Hydrogel Hybrid Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2017-10-26 US disclosed
US-9713527-B2 Multilens intraocular lens system with injectable accommodation material RXSIGHT, INC. (US) 2017-07-25 US disclosed
EP-3192823-A1 USING THE LIGHT ADJUSTABLE LENS (LAL) TO INCREASE THE DEPTH OF FOCUS BY INDUCING TARGETED AMOUNTS OF ASPHERICITY Calhoun Vision Inc (US) 2017-07-19 EP disclosed
EP-3123980-A1 ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION Calhoun Vision, Inc. (US) 2017-02-01 EP disclosed
US-20170020658-A1 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION Calhoun Vision, Inc, (US) 2017-01-26 US disclosed
US-20160324629-A1 USING THE LIGHT ADJUSTABLE LENS (LAL) TO INCREASE THE DEPTH OF FOCUS BY INDUCING TARGETED AMOUNTS OF ASPHERICITY CALHOUN VISION, INC. (US) 2016-11-10 US disclosed
EP-1928353-B1 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION CALHOUN VISION INC (US) 2016-10-26 EP disclosed
EP-1773575-B1 METHOD FOR MAKING ADJUSTABLE COMPOSITIONS CALHOUN VISION INC (US) 2016-10-05 EP disclosed
CN-102762655-B Surface-modified hydrogels and hydrogel microparticles DOW CORNING CORP. (US) 2016-05-11 CN disclosed
US-20160113761-A1 Multilens Intraocular System with Injectable Accommodation Material CALHOUN VISION, INC. (US) 2016-04-28 US disclosed
US-9322960-B2 Method of making a contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2016-04-26 US disclosed
EP-2381770-B1 GEL FORMULA WHICH CAN BE STORED SAFELY FOR A LONG PERIOD WITH AT LEAST TWO ESSENTIALLY UNMIXED HYDROGELS BASF SE (DE) 2016-03-30 EP disclosed
CN-105451984-A Gas-barrier film and method for producing same, and electronic device using same KONICA MINOLTA INC 2016-03-30 CN disclosed
US-9284338-B2 Silicone compound and a use thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-03-15 US disclosed
CN-105246683-A Gas-barrier film and process for producing the same KONICA MINOLTA INC 2016-01-13 CN disclosed
CN-103703029-B Photochromic curable composition TOKUYAMA CORP. (JP) 2016-01-06 CN disclosed
CN-104284776-B Gas barrier film, method for producing gas barrier film, and electronic device KONICA MINOLTA,INC. (JP) 2016-01-06 CN disclosed
CN-101321505-B There is the novel adjustable optical elements strengthening ultraviolet protection CALHOUN VISION, INC. (US) 2015-12-02 CN disclosed
EP-2488895-B1 METHOD OF MAKING A CONTACT LENS SAUFLON CL LTD (GB) 2015-11-25 EP disclosed
US-20150247956-A1 METHOD OF MAKING A CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2015-09-03 US disclosed
US-9119710-B2 Adjustable optical elements with enhanced ultraviolet protection CALHOUN VISION, INC. (US) 2015-09-01 US disclosed
US-9121998-B2 Silicone hydrogel contact lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2015-09-01 US disclosed
US-20150225601-A1 COMPOSITION FOR PATTERN FORMATION, AND PATTERN-FORMING METHOD JSR CORPORATION (JP) 2015-08-13 US disclosed
CN-102666665-B Silicone compositions comprising a swollen silicone gel DOW CORNING 2015-07-22 CN disclosed
US-9057821-B2 Method of making a contact lens SAUFLON CL LIMITED (GB) 2015-06-16 US disclosed
CN-103796827-B Gas barrier film, method for producing gas barrier film, and electronic device KONICA MINOLTA INC 2015-06-10 CN disclosed
US-9005282-B2 Intraocular lens system with injectable accommodation material CALHOUN VISION, INC. (US) 2015-04-14 US disclosed
CN-103269851-B Gas-barrier film and electronic device KONICA MINOLTA INC 2015-04-01 CN disclosed
EP-2452212-B1 MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS BAUSCH & LOMB (US) 2015-03-25 EP disclosed
US-8979261-B2 Silicone hydrogel ophthalmic devices molded in vinyl alcohol copolymer molds and related methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2015-03-17 US disclosed
CN-104284776-A Gas barrier film, method for producing gas barrier film, and electronic device KONICA MINOLTA INC 2015-01-14 CN disclosed
CN-104254584-A Photochromic curable composition TOKUYAMA CORP 2014-12-31 CN disclosed
CN-103025518-B Gas barrier film, process for production of gas barrier film, and electronic device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-10-15 CN disclosed
EP-2756026-A1 USING THE LIGHT ADJUSTABLE LENS (LAL) TO INCREASE THE DEPTH OF FOCUS BY INDUCING TARGETED AMOUNTS OF ASPHERICITY Calhoun Vision Inc (US) 2014-07-23 EP disclosed
CN-103796827-A Gas barrier film, method for producing gas barrier film, and electronic device KONICA MINOLTA INC 2014-05-14 CN disclosed
US-8710156-B2 Process of preparing functionalized polymers via enzymatic catalysis THE UNIVERSITY OF AKRON 2014-04-29 US disclosed
CN-103703029-A Photochromic curable composition TOKUYAMA CORPROATION 2014-04-02 CN disclosed
CN-103635231-A Topical compositions DOW CORNING FRANCE SAS 2014-03-12 CN disclosed
CN-103547347-A Method for coating porous substrates DOW CORNING 2014-01-29 CN disclosed
CN-103547316-A Personal care and health care compositions DOW CORNING 2014-01-29 CN disclosed
US-20140024738-A1 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-01-23 US disclosed
US-20130289153-A1 Using the Light Adjustable Lens (LAL) to Increase the Depth of Focus by Inducing Targeted Amounts of Asphericity CALHOUN VISION INC (US) 2013-10-31 US disclosed
CN-103269851-A Gas-barrier film and electronic device KONICA MINOLTA HOLDINGS INC 2013-08-28 CN disclosed
CN-103237657-A Gas barrier film, method for producing gas barrier film, and electronic device KONICA MINOLTA HOLDINGS INC 2013-08-07 CN disclosed
US-20130197637-A1 METHOD FOR MAKING NOVEL COMPOSITIONS CAPABLE OF POST FABRICATION MODIFICATION CALHOUN VISION, INC (US) 2013-08-01 US disclosed
CN-103055315-A Single phase silicone acrylate formulation DOW CORNING 2013-04-24 CN disclosed
CN-103025518-A Gas barrier film, process for production of gas barrier film, and electronic device KONICA MINOLTA HOLDINGS INC 2013-04-03 CN disclosed
US-20130072591-A1 USING THE LIGHT ADJUSTABLE LENS (LAL) TO INCREASE THE DEPTH OF FOCUS BY INDUCING TARGETED AMOUNTS OF ASPHERICITY RXSIGHT, INC. 2013-03-21 US disclosed
WO-2013039707-A1 USING THE LIGHT ADJUSTABLE LENS (LAL) TO INCREASE THE DEPTH OF FOCUS BY INDUCING TARGETED AMOUNTS OF ASPHERICITY CALHOUN VISION, INC (US) 2013-03-21 WO disclosed
US-8361353-B2 Method for making novel compositions capable of post fabrication modification CALHOUN VISION, INC. (US) 2013-01-29 US disclosed
CN-102781977-A SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS DOW CORNING 2012-11-14 CN disclosed
CN-102762655-A Surface-modified hydrogels and hydrogel microparticles DOW CORNING 2012-10-31 CN disclosed
CN-102666665-A Silicone compositions comprising a swollen silicone gel DOW CORNING 2012-09-12 CN disclosed
CN-102666620-A Hydrophilically-modified silicone compositions DOW CORNING 2012-09-12 CN disclosed
US-8247515-B2 Amphiphilic grafts and co-networks and process for making same THE UNIVERSITY OF AKRON (US) 2012-08-21 US disclosed
CN-101448573-B Borane catalyst complexes with amide functional polymers and curable compositions made therefrom DOW CORNING INC 2012-05-23 CN disclosed
CN-101031411-B Method for making adjustable compositions CALHOUN VISION INC 2012-01-11 CN disclosed
CN-101501088-B Silicone acrylate hybrid compositions DOW CORNING CORP. (US) 2011-11-30 CN disclosed
US-7988285-B2 Light adjustable multifocal lenses CALHOUN VISION, INC. (US) 2011-08-02 US disclosed
US-20110014483-A1 PRIMER COMPOSITION MITSUI CHEMICALS, INC. 2011-01-20 US disclosed
US-7837326-B2 Lenses capable of post-fabrication power modification CALHOUN VISION, INC. (US) 2010-11-23 US disclosed
US-7798644-B2 Lenses capable of post-fabrication power modification CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2010-09-21 US disclosed
US-20100076554-A1 Light Adjustable Multifocal Lenses CALHOUN VISION, INC. (US) 2010-03-25 US disclosed
EP-1459109-B1 LIGHT ADJUSTABLE MULTIFOCAL LENSES CALHOUN VISION INC (US) 2009-08-19 EP disclosed
CN-101501088-A Silicone acrylate hybrid compositions DOW CORNING (US) 2009-08-05 CN disclosed
US-7560499-B2 Initiator and ultraviolet absorber blends for changing lens power by ultraviolet light CALHOUN VISION, INC. (US) 2009-07-14 US disclosed
CN-100497455-C Readjustable optical elements CALHOUN VISION (US) 2009-06-10 CN disclosed
CN-101448573-A Borane catalyst complexes with amide functional polymers and curable compositions made therefrom DOW CORNING (US) 2009-06-03 CN disclosed
EP-2042125-A2 Application of wavefront sensor to lenses capable of post-fabrication power modification California Institute of Technology (US) 2009-04-01 EP disclosed
EP-2001408-A2 MULTILENS INTRAOCULAR LENS SYSTEM WITH INJECTABLE ACCOMMODATION MATERIAL Calhoun Vision, Inc. (US) 2008-12-17 EP disclosed
CN-101321505-A Novel adjustable optical elements with enhanced ultraviolet protection CALHOUN VISION INC (US) 2008-12-10 CN disclosed
CN-101313012-A Initiator and ultraviolet absorber for changing lens optical power by ultraviolet light CALHOUN VISION INC (US) 2008-11-26 CN disclosed
EP-1469772-A4 CUSTOMIZED LENSES CALHOUN VISION INC (US) 2008-10-29 EP disclosed
EP-1928353-A4 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION CALHOUN VISION INC (US) 2008-09-24 EP disclosed
EP-1773575-A4 METHOD FOR MAKING ADJUSTABLE COMPOSITIONS CALHOUN VISION INC (US) 2008-09-24 EP disclosed
EP-1928353-A2 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION Calhoun Vision Inc. (US) 2008-06-11 EP disclosed
US-20080086207-A1 Light Adjustable Multifocal Lenses CALHOUN VISION, INC. (US) 2008-04-10 US disclosed
EP-1907451-A1 INITIATOR AND ULTRAVIOLET ABSORBER FOR CHANGING LENS POWER BY ULTRAVIOLET LIGHT Calhoun Vision, Inc. (US) 2008-04-09 EP disclosed
EP-1379199-A4 COMPOSITION AND METHOD FOR PRODUCING SHAPABLE IMPLANTS i IN VIVO /i AND IMPLANTS PRODUCED THEREBY CALHOUN VISION INC (US) 2008-03-26 EP disclosed
US-20080033547-A1 INTRAOCULAR LENS SYSTEM WITH INJECTABLE ACCOMMODATION MATERIAL CALHOUN VISION, INC (US) 2008-02-07 US disclosed
US-20070260311-A1 LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY 2007-11-08 US disclosed
US-7281795-B2 Light adjustable multifocal lenses CALHOUN VISION, INC. (US) 2007-10-16 US disclosed
WO-2007106796-A2 MULTILENS INTRAOCULAR LENS SYSTEM WITH INJECTABLE ACCOMMODATION MATERIAL CALHOUN VISION, INC. (US) 2007-09-20 WO disclosed
CN-101031411-A Method for making adjustable compositions CALHOUN VISION INC (US) 2007-09-05 CN disclosed
EP-1468044-B1 READJUSTABLE OPTICAL ELEMENTS CALHOUN VISION INC (US) 2007-08-15 EP disclosed
CN-1330980-C Light adjustable multifocal lens CALHOUN VISION CO LTD (US) 2007-08-08 CN disclosed
US-7241009-B2 Crosslinking of silicones presence of functionalized silicones CALHOUN VISION, INC. (US) 2007-07-10 US disclosed
US-20070129802-A1 Composition and method for producing shapable implants in vivo and implants produced thereby CALHOUN VISION, INC. (US) 2007-06-07 US disclosed
EP-1781212-A2 CROSSLINKING OF SILICONES Calhoun Vision, Inc. (US) 2007-05-09 EP disclosed
EP-1459109-A4 LIGHT ADJUSTABLE MULTIFOCAL LENSES CALHOUN VISION INC (US) 2007-05-02 EP disclosed
US-7210783-B2 Lenses capable of post-fabrication power modification CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2007-05-01 US disclosed
EP-1773575-A2 METHOD FOR MAKING ADJUSTABLE COMPOSITIONS Calhoun Vision, Inc. (US) 2007-04-18 EP disclosed
WO-2007030799-A2 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION CALHOUN VISION, INC. (US) 2007-03-15 WO disclosed
US-20070055369-A1 Novel adjustable optical elements with enhanced ultraviolet protection CALHOUN VISION, INC (US) 2007-03-08 US disclosed
EP-1139921-B1 LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INST OF TECHN (US) 2007-03-07 EP disclosed
EP-1755493-A2 INJECTABLE ACCOMMODATION COMPOSITION Calhoun Vision, Inc. (US) 2007-02-28 EP disclosed
US-20070035698-A1 Lenses capable of post-fabrication power modification CALHOUN VISION, INC (US) 2007-02-15 US disclosed
WO-2006135572-A1 INITIATOR AND ULTRAVIOLET ABSORBER FOR CHANGING LENS POWER BY ULTRAVIOLET LIGHT CALHOUN VISION, INC. (US) 2006-12-21 WO disclosed
US-20060273479-A1 Method for making novel compositions capable of post fabrication modification CALHOUN VISION, INC (US) 2006-12-07 US disclosed
CN-1873476-A Light adjustable multifocal lenses CALHOUN VISION INC (US) 2006-12-06 CN disclosed
US-20060271186-A1 Multilens intraocular lens system with injectabe accommodation material CALHOUN VISION, INC (US) 2006-11-30 US disclosed
US-7134755-B2 Customized lenses CALHOUN VISION, INC. (US) 2006-11-14 US disclosed
EP-1703313-A1 Light adjustable multifocal lenses Calhoun Vision, Inc. (US) 2006-09-20 EP disclosed
US-20060142528-A1 Initiator and ultraviolet absorber blends for changing lens power by ultraviolet light CALHOUN VISION, INC (US) 2006-06-29 US disclosed
EP-1266256-B1 APPLICATION OF WAVEFRONT SENSOR TO LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INST OF TECHN (US) 2006-06-21 EP disclosed
EP-1663074-A1 LIGHT ADJUSTABLE MULTIFOCAL LENSES Calhoun Vision, Inc. (US) 2006-06-07 EP disclosed
EP-1658829-A1 Application of wavefront sensor to lenses capable of post-fabrication power modification California Institute of Technology (US) 2006-05-24 EP disclosed
CN-1249454-C Application of wavefront sensor to lenses capable of post-fabrication power modification CALIFORNIA INST OF TECHN (US) 2006-04-05 CN disclosed
WO-2006017488-A2 METHOD FOR MAKING ADJUSTABLE COMPOSITIONS CALHOUN VISION, INC. (US) 2006-02-16 WO disclosed
US-20060027939-A1 Method for making novel compositions capable of post fabrication modification BRAIT AXEL 2006-02-09 US disclosed
WO-2006002201-A2 CROSSLINKING OF SILICONES CALHOUN VISION, INC. (US) 2006-01-05 WO disclosed
WO-2005107649-A2 INJECTABLE ACCOMMODATION COMPOSITION CALHOUN VISION, INC. (US) 2005-11-17 WO disclosed
US-20050246018-A1 Injectable accommodation composition CALHOUN VISION, INC. (US) 2005-11-03 US disclosed
US-20050195361-A1 Customized lenses RXSIGHT, INC. 2005-09-08 US disclosed
US-20050187622-A1 Light adjustable multifocal lenses CALHOUN VISION (US) 2005-08-25 US disclosed
CN-1646588-A Thermoplastic resin composition and engineering plastic composition MITSUBISHI RAYON CO (JP) 2005-07-27 CN disclosed
EP-1468044-A4 READJUSTABLE OPTICAL ELEMENTS CALHOUN VISION INC (US) 2005-07-13 EP disclosed
EP-1470165-A4 INITIATOR AND ULTRAVIOLET ABSORBER FOR CHANGING LENS POWER BY ULTRAVIOLET LIGHT CALHOUN VISION INC (US) 2005-06-15 EP disclosed
CN-1622969-A Readjustable optical elements CALHOUN VISION (US) 2005-06-01 CN disclosed
CN-1618030-A Light adjustable multifocal lenses CALHOUN VISION CO (US) 2005-05-18 CN disclosed
US-20050099597-A1 Light adjustable multifocal lenses CALHOUN VISION (US) 2005-05-12 US disclosed
WO-2005016191-A1 LIGHT ADJUSTABLE MULTIFOCAL LENSES CALHOUN VISION, INC. (US) 2005-02-24 WO disclosed
US-6851804-B2 Readjustable optical elements RXSIGHT, INC. 2005-02-08 US disclosed
US-20050018310-A1 Crosslinking of silicones presence of functionalized silicones RXSIGHT, INC. 2005-01-27 US disclosed
EP-1103574-B1 Emulsions and process of preparing emulsions and oily compositions DOW CORNING TORAY SILICONE (JP) 2005-01-12 EP disclosed
US-6824266-B2 Lenses capable of post-fabrication power modification CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-11-30 US disclosed
US-6813097-B2 Lenses capable of post-fabrication modulus change CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-11-02 US disclosed
EP-1470165-A1 INITIATOR AND ULTRAVIOLET ABSORBER FOR CHANGING LENS POWER BY ULTRAVIOLET LIGHT Calhoun Vision, Inc. (US) 2004-10-27 EP disclosed
EP-1469772-A1 CUSTOMIZED LENSES Calhoun Vision, Inc. (US) 2004-10-27 EP disclosed
EP-1468044-A2 READJUSTABLE OPTICAL ELEMENTS Calhoun Vision Inc. (US) 2004-10-20 EP disclosed
EP-1459109-A1 LIGHT ADJUSTABLE MULTIFOCAL LENSES Calhoun Vision Inc. (US) 2004-09-22 EP disclosed
US-6749632-B2 Application of wavefront sensor to lenses capable of post-fabrication power modification CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-06-15 US disclosed
EP-1379199-A2 COMPOSITION AND METHOD FOR PRODUCING SHAPABLE IMPLANTS i IN VIVO /i AND IMPLANTS PRODUCED THEREBY Calhoun Vision Inc. (US) 2004-01-14 EP disclosed
US-20030174375-A1 Readjustable optical elements CALHOUN VISION, INC. 2003-09-18 US disclosed
US-20030173691-A1 Lenses capable of post-fabrication power modification DEPARTMENT OF VETERANS AFFAIRS 2003-09-18 US disclosed
US-20030176521-A1 To regulate the conditions under which photo-induced reactions occur CALHOUN VISION 2003-09-18 US disclosed
CN-1440551-A Phase contrast variation of photo-induced refractive material CALIFORNIA INST OF TECHN (US) 2003-09-03 CN disclosed
US-20030151831-A1 Light adjustable multifocal lenses CALHOUN VISON 2003-08-14 US disclosed
US-20030151719-A1 Lenses capable of post-fabrication modulus change DEPARTMENT OF VETERANS AFFAIRS 2003-08-14 US disclosed
WO-2003058287-A2 OPTICAL ELEMENTS RE-ADJUSTABLE WITH UV-LIGHT CALHOUN VISION (US) 2003-07-17 WO disclosed
WO-2003057022-A1 CUSTOMIZED LENSES CALHOUN VISION, INC. (US) 2003-07-17 WO disclosed
WO-2003057742-A1 INITIATOR AND ULTRAVIOLET ABSORBER FOR CHANGING LENS POWER BY ULTRAVIOLET LIGHT CALHOUN VISION, INC. (US) 2003-07-17 WO disclosed
WO-2003058296-A1 LIGHT ADJUSTABLE MULTIFOCAL LENSES CALHOUN VISION (US) 2003-07-17 WO disclosed
US-20030128336-A1 Customized lenses JETHMALANI JAGDISH M (US) 2003-07-10 US disclosed
CN-1429090-A Application of wavefront sensor to lenses capable of post-fabrication power modification CALIFORNIA INST OF TECHN (US) 2003-07-09 CN disclosed
US-20030093150-A1 Lanses capable of post-fabrication power modification DEPARTMENT OF VETERANS AFFAIRS 2003-05-15 US disclosed
US-20030090624-A1 Lenses capable of post-fabrication power modification REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2003-05-15 US disclosed
US-20030090013-A1 Lenses capable of post-fabrication power modification REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2003-05-15 US disclosed
US-20030048411-A1 Intraoccular lenses capable of in vivo power adjustment and method for same REGENT OF THE UNIVERSITY CALIFORNIA OF THE 2003-03-13 US disclosed
WO-2003011194-A1 INTRAOCCULAR LENSES WITH POWER ADJUSTABILITY IN VIVO CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-02-13 WO disclosed
EP-1281176-A2 PHASE CONTRAST VARIATION OF A PHOTO-INDUCED REFRACTIVE MATERIAL California Institute Of Technology (US) 2003-02-05 EP disclosed
EP-1266256-A2 APPLICATION OF WAVEFRONT SENSOR TO LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION California Institute of Technology (US) 2002-12-18 EP disclosed
US-20020169505-A1 Composition and method for producing shapable implants in vivo and implants produced thereby JETHMALANI JAGDISH M (US) 2002-11-14 US disclosed
US-20020167735-A1 Optical elements capable of post-fabrication modulus change CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-11-14 US disclosed
WO-2002076338-A2 COMPOSITION AND METHOD FOR PRODUCING SHAPABLE IMPLANTS IN VIVO AND IMPLANTS PRODUCED THEREBY CALHOUN VISION (US) 2002-10-03 WO disclosed
US-6450642-B1 Lenses capable of post-fabrication power modification CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-09-17 US disclosed
US-6388005-B1 CROSSLINKED PARTICLES IN DROPS OF SILICONE OIL DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-05-14 US disclosed
US-20020042004-A1 Phase contrast variation of a photo-induced refractive material CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-04-11 US disclosed
US-20020016629-A1 Application of wavefront sensor to lenses capable of post-fabrication power modification DEPARTMENT OF VETERANS AFFAIRS 2002-02-07 US disclosed
WO-2001086647-A2 PHASE CONTRAST VARIATION OF A PHOTO-INDUCED REFRACTIVE MATERIAL CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2001-11-15 WO disclosed
EP-1139921-A1 LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2001-10-10 EP disclosed
WO-2001071411-A2 APPLICATION OF WAVEFRONT SENSOR TO LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2001-09-27 WO disclosed
EP-1103574-A1 Emulsions and process of preparing emulsions and oily compositions Dow Corning Toray Silicone Co., Ltd. (JP) 2001-05-30 EP disclosed
WO-2000041650-A1 LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-07-20 WO disclosed
CN-1178808-A Resin composition, chlorine containing resin composition containing resin composition and its formed materials KUREHA KAGAKU IND CO LTD (JP) 1998-04-15 CN disclosed
EP-0186705-B1 TERMINAL CLUSTER ACRYLATE SILICONES LOCTITE CORPORATION (US) 1989-01-25 EP disclosed
US-4760122-A Acrylated polyorganosiloxane LOCTITE CORPORATION (US) 1988-07-26 US disclosed
US-4728709-A Terminal cluster vinyl silicones and acrylate cluster silicones therefrom LOCTITE CORPORATION (US) 1988-03-01 US disclosed
EP-0186705-A1 TERMINAL CLUSTER ACRYLATE SILICONES. LOCTITE CORP (US) 1986-07-09 EP disclosed
US-4575546-A Terminal cluster vinyl silicones and acrylate cluster silicones therefrom LOCTITE CORPORATION (US) 1986-03-11 US disclosed
US-4575545-A Terminal cluster acrylate silicones LOCTITE CORPORATION (US) 1986-03-11 US disclosed
WO-1986000322-A1 TERMINAL CLUSTER ACRYLATE SILICONES LOCTITE CORPORATION (US) 1986-01-16 WO disclosed
WO-1983001777-A1 IMPROVED OXYGEN PERMEABLE HARD AND SEMI-HARD CONTACT LENS COMPOSITIONS, METHODS AND ARTICLES OF MANUFACTURE TSUETAKI GEORGE F (US) 1983-05-26 WO disclosed
WO-1983001777-A1 IMPROVED OXYGEN PERMEABLE HARD AND SEMI-HARD CONTACT LENS COMPOSITIONS, METHODS AND ARTICLES OF MANUFACTURE TSUETAKI GEORGE F (US) 1983-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10470874-B2 Adjustable optical elements with enhanced ultraviolet protection UACA, ERCC4, CRYAB TSHR 2605/4885THRB 4404/4885POLB 3719/4885
US-20190262125-A9 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION UACA, ERCC4, CRYZ TSHR 2704/4885THRB 4591/4885POLB 4242/4885
US-20170020658-A1 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION UACA, ERCC4, CRYZ TSHR 2704/4885THRB 4591/4885POLB 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.