Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490786 | 0.94 | MEN1 (0.59) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9204780 | 0.91 | LTB4R (0.55) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1592618 | 0.87 | HSP90AB1 (0.61) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11891941 | 0.86 | MEN1 (0.50) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4852083 | 0.86 | MEN1 (0.56) | LTB4RLTB4R2MEN1KMT2AALOX5 | |
| SCHEMBL348012 | 0.85 | MRGPRX4 (0.52) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10077742 | 0.85 | PPARG (0.53) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2968381 | 0.85 | MEN1 (0.49) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1593105 | 0.84 | MEN1 (0.51) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2848161 | 0.84 | MAOB (0.60) | LTB4RLTB4R2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092554-A1 | 1,3,5 TRI-SUBTITUTED BENZENES FOR TREATMENT OF ALZHEIMER'S DISEASE AND OTHER DISORDERS | ENVIVO PHARMACEUTICALS, INC. | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092554-A1 | 1,3,5 TRI-SUBTITUTED BENZENES FOR TREATMENT OF ALZHEIMER'S DISEASE AND OTHER DISORDERS | PSEN1, PSEN2, BACE1 | LTB4R 1814/4885LTB4R2 1969/4885MEN1 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.