SCHEMBL1270436

SCHEMBL1270436

O=C(O)C(S)Cc1ccc(O)cc1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.60
CA2 P00918 1/20 0.48
CAMK2A Q9UQM7 1/20 0.48
MME P08473 5/20 0.48
ACE P12821 3/20 0.48
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
POLB P06746 1/20 0.46
TAAR1 Q96RJ0 2/20 0.45
SLC6A2 P23975 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11213177 0.91 MME (0.53) SLC7A5MMEACECPA1ACE2
SCHEMBL9659004 0.83 PPARG (0.56) MME
SCHEMBL4838500 0.83 MME (0.65) SLC7A5MMEACECPA1ACE2
SCHEMBL498453 0.83 MME (0.65) SLC7A5MMEACECPA1ACE2
SCHEMBL3007531 0.82 MME (0.68) MME
Hydrochloric Acid SCHEMBL7054010 0.81 MME (0.62) SLC7A5MMEACECPA1ACE2
SCHEMBL490650 0.80 SLC7A5 (0.67) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL1127788 0.80 MDM2 (0.53) SLC7A5MMEACECPA1ACE2
SCHEMBL10436391 0.78 CYP1A2 (0.68) SLC7A5CA2CAMK2AMMECPA1
SCHEMBL5746242 0.77 LDHA (0.71)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459576-A1 LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER Chemtura Corporation (US) 2012-06-06 EP disclosed
WO-2011014477-A1 LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
CN-1239591-C Phenolefree stablization of polyolefins CLARIANT FINANCE LTD BVI (GB) 2006-02-01 CN disclosed
CN-1538989-A Property enhancement of polyamides by co-condensation with light stabilizers �����ﰲ�ز���(BVI)���޹�˾ 2004-10-20 CN disclosed
CN-1538987-A Phenolefree stablization of polyolefins �����ﰲ�ز���(BVI)���޹�˾ 2004-10-20 CN disclosed
EP-1268426-A1 4-FORMYL AMINO-N-METHYLPIPERIDINE DERIVATIVES, THE USE THEREOF AS STABILISERS AND ORGANIC MATERIAL STABILISED THEREWITH BASF AKTIENGESELLSCHAFT (DE) 2003-01-02 EP disclosed
EP-1155098-A1 LIQUID CRYSTALLINE SUBSTANCE MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2001-11-21 EP disclosed
WO-2001074777-A1 4-FORMYL AMINO-N-METHYLPIPERIDINE DERIVATIVES, THE USE THEREOF AS STABILISERS AND ORGANIC MATERIAL STABILISED THEREWITH BASF AKTIENGESELLSCHAFT (DE) 2001-10-11 WO disclosed
WO-2000047694-A1 LIQUID CRYSTALLINE SUBSTANCE MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2000-08-17 WO disclosed
EP-0435828-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1991-07-03 EP disclosed
EP-0176106-B1 N,N',N-TRIS((2,2,6,6-TETRAMETHYL-4-PIPERIDYL)TRIAZINYL)-UNDECANE TRIAMINES AS STABILIZERS FOR SYNTHETIC POLYMERS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1990-11-22 EP disclosed