SCHEMBL12704653

SCHEMBL12704653

C1=NC[C@H]2C[C@@H]12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11100092 1.00
SCHEMBL245584 0.69
SCHEMBL24190367 0.69
SCHEMBL24831577 0.67
SCHEMBL24862264 0.61
SCHEMBL376062 0.51
SCHEMBL1224717 0.45
SCHEMBL31667872 0.41
Adamantane SCHEMBL8848421 0.38 CYP2C9 (0.43)
SCHEMBL9383231 0.38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023168827-A1 SYNTHESIS METHOD FOR PAXLOVID INTERMEDIATE 杭州国瑞生物科技有限公司 2023-09-14 WO disclosed
US-20110092716-A1 DEHYDROHALOGENATION PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN PROVIDING 6,6-DIMETHYL-3-AZABICYCLO-[3.1.0]- HEXANE COMPOUNDS KWOK DAW-LONG 2011-04-21 US disclosed