⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24190367 | 1.00 | — | — | |
| SCHEMBL1571046 | 0.95 | — | — | |
| SCHEMBL1571226 | 0.95 | — | — | |
| SCHEMBL2744247 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL1570939 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL30457850 | 0.92 | — | — | |
| SCHEMBL244154 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL362734 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL17776508 | 0.72 | — | — | |
| SCHEMBL11100092 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912576-A1 | PROCESS FOR SYNTHESIZING CARBAPENEM ANTIBIOTICS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | claimed |
| WO-1998002439-A1 | PROCESS FOR SYNTHESIZING CARBAPENEM ANTIBIOTICS | MERCK & CO., INC. (US) | 1998-01-22 | — | — | WO | claimed |
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | claimed |
| WO-2024109688-A1 | PYRROLE FUSED RING DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 成都百裕制药股份有限公司 | 2024-05-30 | — | — | WO | disclosed |
| EP-3484982-B1 | POLYESTER DISPERSANTS, SYNTHESIS AND USE THEREOF | CHEVRON ORONITE CO (US) | 2024-05-22 | — | — | EP | disclosed |
| CN-117916215-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11787788-B2 | Benzimidazole derivatives, and pharmaceutical compositions and methods of use thereof | CAPELLA THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230271938-A1 | BENZIMIDAZOLES FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES | CAPELLA THERAPEUTICS, INC. | 2023-08-31 | — | — | US | disclosed |
| US-11713322-B2 | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | CAPELLA THERAPEUTICS, INC. (US) | 2023-08-01 | — | — | US | disclosed |
| US-20230234909-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | NUCMITO PHARMACEUTICALS CO. LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| CN-116472034-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-1753428-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005110410-A2 | KINASE INHIBITORS AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | disclosed |
| EP-0899259-B1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-1315761-A1 | CROSSLINKABLE POLYMERIC COMPOSITIONS AND USE THEREOF | 3M Innovative Properties Company (US) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002020625-A1 | CROSSLINKABLE POLYMERIC COMPOSITIONS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-03-14 | — | — | WO | disclosed |
| EP-0912576-A1 | PROCESS FOR SYNTHESIZING CARBAPENEM ANTIBIOTICS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0899259-A1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-03-03 | — | — | EP | disclosed |
| WO-1998002439-A1 | PROCESS FOR SYNTHESIZING CARBAPENEM ANTIBIOTICS | MERCK & CO., INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | disclosed |