Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13148678 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL351141 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL30175750 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL5076534 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL351140 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL5972018 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL14012093 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL14175285 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL3163678 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD | |
| SCHEMBL18688 | 1.00 | HIF1A (0.44) | HIF1APTGS2LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311321-A2 | Insecticide on the basis of neonicotinoids and selected strobilurins | Bayer CropScience AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2301355-A2 | Insecticides based on nicotinoides and specific strobilurines | Bayer CropScience AG (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-2301354-A2 | Insecticide on the basis of neonicotinoids and selected strobilurins | Bayer CropScience AG (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-2127523-A2 | Insecticide on the basis of neonicotinoids and selected strobilurins | Bayer CropScience AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| US-20080274882-A1 | Insecticides Based on Selected Neonicotinoids and Strobilurins | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274882-A1 | Insecticides Based on Selected Neonicotinoids and Strobilurins | STMN2, STMN1, DDX6 | HIF1A 4622/4885PTGS2 1207/4885LMNA 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.