⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270472 | 1.00 | — | — | |
| SCHEMBL15365002 | 0.82 | EP300 (0.54) | — | |
| SCHEMBL15365004 | 0.82 | EP300 (0.54) | — | |
| SCHEMBL289331 | 0.80 | EP300 (0.57) | — | |
| SCHEMBL28049691 | 0.80 | EP300 (0.57) | — | |
| SCHEMBL29186895 | 0.80 | EP300 (0.57) | — | |
| SCHEMBL289328 | 0.80 | EP300 (0.57) | — | |
| SCHEMBL5310111 | 0.77 | — | — | |
| SCHEMBL16445474 | 0.74 | — | — | |
| SCHEMBL11304646 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106645471-B | Double UV check method that is a kind of while measuring three kinds of toxicity aldehydes in edible vegetable oil | 华南理工大学 | 2019-06-18 | — | — | CN | claimed |
| EP-2252897-A2 | METHOD FOR DIRECT DETECTION OF ISCHAEMIA-MODIFIED ALBUMIN USING A PARTNER FOR BINDING TO AN ALDEHYDE DERIVATIVE RESULTING FROM THE PEROXIDATION OF LIPIDS IN BOUND FORM | Biomérieux (FR) | 2010-11-24 | — | — | EP | claimed |
| WO-2009115756-A2 | METHOD FOR DIRECT DETECTION OF ISCHAEMIA-MODIFIED ALBUMIN USING A PARTNER FOR BINDING TO AN ALDEHYDE DERIVATIVE RESULTING FROM THE PEROXIDATION OF LIPIDS IN BOUND FORM | bioMérieux (FR) | 2009-09-24 | — | — | WO | claimed |
| US-20230228744-A1 | DRY EYE DISEASE BIOMARKERS AND THEIR USE FOR TREATMENT | ALDEYRA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| CN-115943314-A | Biomarkers for dry eye disease and therapeutic uses thereof | 奥尔德拉医疗公司 | 2023-04-07 | — | — | CN | disclosed |
| US-20110039353-A1 | METHOD FOR DIRECT DETECTION OF ISCHEMIA-MODIFIED ALBUMIN USING A PARTNER FOR BINDING TO AN ALDEHYDE DERIVATIVE RESULTING FROM THE PEROXIDATION OF LIPIDS IN BOUND FORM | BIOMERIEUX (FR) | 2011-02-17 | — | — | US | disclosed |
| EP-2252897-A2 | METHOD FOR DIRECT DETECTION OF ISCHAEMIA-MODIFIED ALBUMIN USING A PARTNER FOR BINDING TO AN ALDEHYDE DERIVATIVE RESULTING FROM THE PEROXIDATION OF LIPIDS IN BOUND FORM | Biomérieux (FR) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009115756-A2 | METHOD FOR DIRECT DETECTION OF ISCHAEMIA-MODIFIED ALBUMIN USING A PARTNER FOR BINDING TO AN ALDEHYDE DERIVATIVE RESULTING FROM THE PEROXIDATION OF LIPIDS IN BOUND FORM | bioMérieux (FR) | 2009-09-24 | — | — | WO | disclosed |