SCHEMBL289328

SCHEMBL289328

CCCCCC/C=C(\O)C=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.57
TSHR P16473 1/20 0.52
FAAH O00519 3/20 0.46
TRPV1 Q8NER1 1/20 0.46
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
MAPT P10636 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
TOP1 P11387 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28049691 1.00 EP300 (0.57) EP300TSHRFAAHTRPV1TERT
SCHEMBL289331 1.00 EP300 (0.57) EP300TSHRFAAHTRPV1TERT
SCHEMBL29186895 1.00 EP300 (0.57) EP300TSHRFAAHTRPV1TERT
SCHEMBL15365004 0.98 EP300 (0.54) EP300TSHRFAAHTRPV1TERT
SCHEMBL15365002 0.98 EP300 (0.54) EP300TSHRFAAHTRPV1TERT
Pyrrole SCHEMBL989904 0.87 EP300 (0.46) EP300TSHRFAAHTRPV1TERT
Pyrrole SCHEMBL989906 0.87 EP300 (0.46) EP300TSHRFAAHTRPV1TERT
SCHEMBL1270472 0.80
SCHEMBL1270469 0.80
SCHEMBL6577157 0.79 EP300 (0.50) EP300TSHRFAAHTRPV1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113784629-B Method for preparing plant extract composition 嘉吉公司 2024-12-27 CN claimed
EP-4363043-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS Novocure GmbH (CH) 2024-05-08 EP claimed
US-11931391-B2 Methods for making botanical extract composition CARGILL, INCORPORATED (US) 2024-03-19 US claimed
CN-117580614-A Compositions and methods for increasing sensitivity of cancer cells to alternating electric fields 诺沃库勒有限责任公司 2024-02-20 CN claimed
US-20230364270-A1 LIPOSOME-ASSISTED IMAGING OF VASCULAR INFLAMMATION HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ (FI) 2023-11-16 US claimed
EP-4192520-A1 LIPOSOME-ASSISTED IMAGING OF VASCULAR INFLAMMATION Helsingin Ja Uudenmaan Sairaanhoitopiirin Kuntayhtymä (FI) 2023-06-14 EP claimed
EP-4188380-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS Novocure GmbH (CH) 2023-06-07 EP claimed
CN-116096432-A Liposome-assisted imaging of vascular inflammation 赫尔辛基和乌登曼护理区市政协会 2023-05-09 CN claimed
US-20230001193-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS BIOPHARMA CREDIT PLC (GB) 2023-01-05 US claimed
WO-2023275649-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2023-01-05 WO claimed
US-20050272094-A1 Purified antigen for Alzheimer's disease and methods of obtaining and using same MOLECULAR GERIATRICS CORPORATION 2005-12-08 US claimed
WO-2005023864-A1 PEPTIDE-BASED IMMUNIZATION THERAPY FOR TREATMENT OF ATHEROSCLEROSIS FORSKARPATENT I SYD AB (SE) 2005-03-17 WO claimed
JP-2004529143-A 2004-09-24 JP claimed
EP-1383526-A1 PEPTIDE-BASED IMMUNIZATION THERAPY FOR TREATMENT OF ATHEROSCLEROSIS AND DEVELOPMENT OF PEPTIDE-BASED ASSAY FOR DETERMINATION OF IMMUNE RESPONSES AGAINST OXIDIZED LOW DENSITY LIPOPROTEIN Forskarpatent I SYD (SE) 2004-01-28 EP claimed
US-20030113896-A1 Purified antigen for Alzheimer's disease and methods of obtaining and using same ZINKOWSKI RAYMOND P (US) 2003-06-19 US claimed
US-20030105003-A1 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein CARDIOVAX, LLC 2003-06-05 US claimed
WO-2002080954-A1 PEPTIDE-BASED IMMUNIZATION THERAPY FOR TREATMENT OF ATHEROSCLEROSIS AND DEVELOPMENT OF PEPTIDE-BASED ASSAY FOR DETERMINATION OF IMMUNE RESPONSES AGAINST OXIDIZED LOW DENSITY LIPOPROTEIN FORSKARPATENT I SYD (SE) 2002-10-17 WO claimed
EP-1189937-A1 PURIFIED ANTIGEN FOR ALZHEIMER'S DISEASE, AND METHODS OF OBTAINING AND USING SAME MOLECULAR GERIATRICS CORPORATION (US) 2002-03-27 EP claimed
US-20020002270-A1 PURIFIED ANTIGEN FOR ALZHEIMER'S DISEASE, AND METHODS OF OBTAINING AND USING SAME MOLECULAR GERIATRICS CORPORATION 2002-01-03 US claimed
WO-2000078807-A1 PURIFIED ANTIGEN FOR ALZHEIMER'S DISEASE, AND METHODS OF OBTAINING AND USING SAME MOLECULAR GERIATRICS CORPORATION (US) 2000-12-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105003-A1 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein APOB, LDLR, APOL1 EP300 4001/4885TSHR 2812/4885FAAH 3167/4885
US-11931391-B2 Methods for making botanical extract composition ME1, SLC16A7, MCCC2 EP300 2947/4885TSHR 4640/4885FAAH 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.