Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 3/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55687 | 0.95 | SORT1 (0.66) | SORT1MAPK14LSSAPEX1PPARA | |
| SCHEMBL11056196 | 0.83 | KMT2A (0.66) | APEX1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6722952 | 0.78 | SORT1 (0.60) | SORT1MAPK14LSSAPEX1PPARA | |
| SCHEMBL5051133 | 0.76 | KMT2A (0.56) | APEX1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL16351644 | 0.76 | KMT2A (0.56) | APEX1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL15903272 | 0.75 | SORT1 (0.90) | SORT1APEX1PPARAKMT2AASPH | |
| SCHEMBL15903271 | 0.75 | SORT1 (1.00) | SORT1 | |
| SCHEMBL6722982 | 0.75 | SORT1 (0.62) | SORT1MAPK14LSSAPEX1PPARA | |
| SCHEMBL2634030 | 0.74 | MAPK14 (0.76) | MAPK14LSSPPARAPPARGEPHX2 | |
| SCHEMBL26625301 | 0.74 | SORT1 (0.54) | SORT1MAPK14LSSAPEX1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8963126-B2 | Low-voltage, N-channel transistors including a hybrid semiconductor-dielectric material | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-02-24 | — | — | US | disclosed |
| US-20110024727-A1 | LOW-VOLTAGE, N-CHANNEL HYBRID TRANSISTORS | THE JOHN HOPKINS UNIVERSITY (US) | 2011-02-03 | — | — | US | disclosed |