Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.57 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12707091 | 0.94 | KDM4E (0.48) | EHMT2KDM4EPTGER4MCHR1IRAK4 | |
| SCHEMBL12707148 | 0.92 | KDM4E (0.46) | EHMT2KDM4EPTGER4MCHR1IRAK4 | |
| SCHEMBL12707204 | 0.90 | EHMT2 (0.59) | EHMT2EHMT1HDAC6PTGER4ADORA2A | |
| SCHEMBL12707152 | 0.90 | ADORA2A (0.51) | EHMT2KDM4EPTGER4MCHR1IRAK4 | |
| SCHEMBL12707113 | 0.90 | EHMT2 (0.53) | EHMT2EHMT1HDAC6PTGER4ADORA2A | |
| SCHEMBL12707153 | 0.89 | EHMT2 (0.44) | EHMT2KDM4EPTGER4MCHR1IRAK4 | |
| SCHEMBL12707150 | 0.88 | CNR2 (0.46) | EHMT2KDM4EPTGER4MCHR1IRAK4 | |
| SCHEMBL12707177 | 0.88 | EHMT2 (0.56) | EHMT2EHMT1HDAC6PTGER4ADORA2A | |
| SCHEMBL12707098 | 0.88 | EHMT2 (0.56) | EHMT2EHMT1KDM4ETLR7PTGER4 | |
| SCHEMBL12707180 | 0.88 | EHMT2 (0.54) | EHMT2EHMT1HDAC6PTGER4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383662-B2 | Bicyclic heteroaryl compounds | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-8383662-B2 | Bicyclic heteroaryl compounds | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20110082143-A1 | Bicyclic Heteroaryl Compounds | NATIONAL TAIWAN UNIVERSITY (TW) | 2011-04-07 | — | — | US | disclosed |
| US-20110082143-A1 | Bicyclic Heteroaryl Compounds | NATIONAL TAIWAN UNIVERSITY (TW) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082143-A1 | Bicyclic Heteroaryl Compounds | SDHA, CYP2F1, PAICS | EHMT2 3089/4885EHMT1 3599/4885HDAC6 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.