Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910876 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1TDP1 | |
| SCHEMBL6905685 | 0.72 | KDM4E (0.36) | KDM4EALDH1A1TDP1 | |
| SCHEMBL1525278 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1TDP1 | |
| SCHEMBL6911566 | 0.69 | KDM4E (0.35) | KDM4EALDH1A1TDP1 | |
| SCHEMBL12532460 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1TDP1 | |
| SCHEMBL18030165 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1TDP1 | |
| SCHEMBL27311648 | 0.67 | KDM4E (0.40) | KDM4EALDH1A1TDP1 | |
| SCHEMBL765883 | 0.66 | KDM4E (0.35) | KDM4EALDH1A1TDP1 | |
| SCHEMBL13354403 | 0.65 | KDM4E (0.37) | KDM4EALDH1A1TDP1 | |
| SCHEMBL7109470 | 0.65 | KDM4E (0.34) | KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951724-B1 | FUSED BICYCLIC mTOR INHIBITORS | OSI PHARM INC (US) | 2011-04-27 | — | — | EP | disclosed |