Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 20/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711841 | 0.97 | BDKRB2 (0.53) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711915 | 0.88 | BDKRB2 (0.55) | BDKRB2 | |
| SCHEMBL12711896 | 0.86 | BDKRB2 (0.56) | BDKRB2 | |
| SCHEMBL12712383 | 0.86 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL12712398 | 0.86 | BDKRB2 (0.51) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711892 | 0.86 | BDKRB2 (0.59) | BDKRB2 | |
| SCHEMBL12711480 | 0.86 | BDKRB2 (0.54) | BDKRB2 | |
| SCHEMBL12711357 | 0.85 | BDKRB2 (0.52) | BDKRB2 | |
| SCHEMBL12711481 | 0.84 | BDKRB2 (0.54) | BDKRB2 | |
| SCHEMBL13092999 | 0.84 | BDKRB2 (0.51) | BDKRB2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305668-A1 | 8-oxy-quinoline derivatives as bradykinin B2 receptor modulators | Jerini AG (DE) | 2011-04-06 | — | — | EP | disclosed |