Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 9/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | RORC | P51449 | 8/20 | 0.37 |
| ▸ | CD38 | P28907 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712279 | 0.86 | BDKRB2 (0.67) | BDKRB2CYP3A4CYP2C19CD38KCNH2 | |
| SCHEMBL13093101 | 0.84 | BDKRB2 (0.63) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL12711474 | 0.83 | BDKRB2 (0.64) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL12711841 | 0.83 | BDKRB2 (0.53) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL13145580 | 0.81 | BDKRB2 (0.67) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL13145562 | 0.81 | BDKRB2 (0.99) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711889 | 0.81 | BDKRB2 (0.63) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL13145528 | 0.81 | BDKRB2 (0.68) | BDKRB2CYP3A4CYP2C19RORC | |
| SCHEMBL13145530 | 0.81 | BDKRB2 (1.00) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711476 | 0.80 | BDKRB2 (0.64) | BDKRB2CYP3A4CYP2C19RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305668-A1 | 8-oxy-quinoline derivatives as bradykinin B2 receptor modulators | Jerini AG (DE) | 2011-04-06 | — | — | EP | disclosed |