Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 16/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711378 | 0.93 | BDKRB2 (0.52) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL13093439 | 0.93 | BDKRB2 (0.52) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711833 | 0.92 | BDKRB2 (0.53) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711482 | 0.91 | BDKRB2 (0.53) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12711486 | 0.89 | BDKRB2 (0.54) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12712309 | 0.87 | BDKRB2 (0.52) | BDKRB2CYP3A4 | |
| SCHEMBL12711865 | 0.87 | BDKRB2 (0.52) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL12712285 | 0.86 | BDKRB2 (0.45) | BDKRB2CYP3A4 | |
| SCHEMBL13093137 | 0.86 | BDKRB2 (0.53) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL13093434 | 0.86 | BDKRB2 (0.49) | BDKRB2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305668-A1 | 8-oxy-quinoline derivatives as bradykinin B2 receptor modulators | Jerini AG (DE) | 2011-04-06 | — | — | EP | disclosed |