SCHEMBL12714432

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13066266	0.91	ALDH1A1 (0.58)	TDP1HPGDALDH1A1EGFRLMNA
	SCHEMBL31238859	0.89	MAPT (0.58)	TDP1EGFRLMNAMAPTKDM4E
	SCHEMBL12836646	0.84	CA1 (0.61)	HPGDALDH1A1EGFRLMNAMAPT
	SCHEMBL26571944	0.84	TDP1 (0.61)	TDP1HPGDALDH1A1EGFRLMNA
	SCHEMBL19111160	0.84	EGFR (0.68)	TDP1HPGDALDH1A1EGFRLMNA
	SCHEMBL14635301	0.83	MAPT (0.54)	HPGDALDH1A1EGFRMAPTKDM4E
	SCHEMBL29788226	0.83	MAPT (0.54)	HPGDALDH1A1EGFRMAPTKDM4E
	SCHEMBL2946107	0.83	PTGS1 (0.55)	HPGDALDH1A1EGFRLMNAMAPT
	SCHEMBL2952031	0.82	EGFR (0.51)	EGFRMAPTKDM4ENPC1RAB9A
	SCHEMBL17707305	0.81	TDP1 (0.58)	TDP1HPGDALDH1A1EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.