Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057752 | 1.00 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13590783 | 0.90 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12299524 | 0.89 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12299525 | 0.88 | BCL6 (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12299528 | 0.88 | BCL6 (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12998478 | 0.87 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12299523 | 0.84 | KMT2A (0.44) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12299580 | 0.84 | NPC1 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12299639 | 0.84 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2606002 | 0.83 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923540-B2 | 2-[[1-[[(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)amino]carbonyl]-2-oxopropyl]azo]-benzoic acid and a process for its preparation | BASF SE (DE) | 2011-04-12 | — | — | US | disclosed |
| US-7923540-B2 | 2-[[1-[[(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)amino]carbonyl]-2-oxopropyl]azo]-benzoic acid and a process for its preparation | BASF SE (DE) | 2011-04-12 | — | — | US | disclosed |
| EP-1976937-B1 | 2-[[1-[[(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-5-YL)AMINO]CARBONYL]-2-OXOPROPYL]AZO]-BENZOIC ACID AND A PROCESS FOR ITS PREPARATION | BASF SE (DE) | 2009-12-02 | — | — | EP | disclosed |
| US-20090012305-A1 | 2-[[1-[[(2,3-Dihydro-2-Oxo-1H-Benzimidazol-5-Yl)Amino]Carbonyl]-2-Oxopropyl]Azo]-Benzoic Acid and a Process For Its Preparation | BASF SE (DE) | 2009-01-08 | — | — | US | disclosed |
| US-20090012305-A1 | 2-[[1-[[(2,3-Dihydro-2-Oxo-1H-Benzimidazol-5-Yl)Amino]Carbonyl]-2-Oxopropyl]Azo]-Benzoic Acid and a Process For Its Preparation | BASF SE (DE) | 2009-01-08 | — | — | US | disclosed |
| WO-2007082813-A1 | 2-[[1-[[(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-5-YL)AMINO]CARBONYL]-2-OXOPROPYL]AZO]-BENZOIC ACID AND A PROCESS FOR ITS PREPARATION | CIBA HOLDING INC. (CH) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012305-A1 | 2-[[1-[[(2,3-Dihydro-2-Oxo-1H-Benzimidazol-5-Yl)Amino]Carbonyl]-2-Oxopropyl]Azo]-Benzoic Acid and a Process For Its Preparation | IK, TYR, RB1 | MAPT 417/4885ALDH1A1 1098/4885MEN1 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.