SCHEMBL12299528

SCHEMBL12299528

CC(=O)/C(=N/Nc1cc(C(=O)O)ccc1C(=O)O)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCL6 P41182 1/20 0.47
BCOR Q6W2J9 1/20 0.47
ALDH1A1 P00352 7/20 0.45
KDM4E B2RXH2 5/20 0.45
RAB9A P51151 1/20 0.45
MAPT P10636 9/20 0.42
MAPK1 P28482 1/20 0.42
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
GAA P10253 2/20 0.40
RXFP1 Q9HBX9 1/20 0.39
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14528612 0.93 BCL6 (0.44) BCL6BCORALDH1A1KDM4ERAB9A
SCHEMBL12299525 0.92 BCL6 (0.49) BCL6BCORALDH1A1KDM4ERAB9A
SCHEMBL12299499 0.88 MAPT (0.51) BCL6BCORALDH1A1KDM4ERAB9A
SCHEMBL13057752 0.88 MAPT (0.49) ALDH1A1KDM4ERAB9AMAPTMAPK1
SCHEMBL12715367 0.88 MAPT (0.49) ALDH1A1KDM4ERAB9AMAPTMAPK1
SCHEMBL12299494 0.87 MAPT (0.47) BCL6BCORALDH1A1KDM4ERAB9A
SCHEMBL12299594 0.86 MAPT (0.42) ALDH1A1KDM4ERAB9AMAPTMAPK1
SCHEMBL12299524 0.85 MAPT (0.44) ALDH1A1KDM4ERAB9AMAPTMAPK1
SCHEMBL11913348 0.84 MAPT (0.46) BCL6BCORALDH1A1KDM4ERAB9A
SCHEMBL12299595 0.84 MAPT (0.49) BCL6BCORALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
EP-1790696-A1 Non-aqueous pigment dispersions containing specific dispersion synergists Agfa Graphics N.V. (BE) 2007-05-30 EP disclosed