Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938402 | 0.83 | RAF1 (0.58) | MEN1KMT2ASMN1; SMN2POLBIGF1R | |
| SCHEMBL4185779 | 0.79 | RAF1 (0.58) | MEN1KMT2AIGF1RKDR | |
| SCHEMBL2328292 | 0.79 | RAF1 (0.49) | MEN1KMT2ASMN1; SMN2POLBIGF1R | |
| SCHEMBL4173358 | 0.79 | RAF1 (0.52) | MEN1KMT2ASMN1; SMN2IGF1RKDR | |
| SCHEMBL4172684 | 0.78 | RAF1 (0.48) | MEN1KMT2ASMN1; SMN2IGF1RKDR | |
| SCHEMBL257963 | 0.78 | RAF1 (0.59) | MEN1KMT2AGSK3BMAOAKDR | |
| SCHEMBL261957 | 0.78 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL12749714 | 0.77 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2POLBIGF1R | |
| SCHEMBL7574156 | 0.74 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2HPGDTSHR | |
| SCHEMBL1506401 | 0.73 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928239-B2 | Anticarcinogenic agents | BAYER HEALTHCARE LLC (US) | 2011-04-19 | — | — | US | disclosed |