Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640912 | 0.85 | HTR2C (0.47) | HTR2CL3MBTL1KDM1AEPHX1HRH3 | |
| SCHEMBL14744263 | 0.78 | SCN10A (0.44) | HTR2CL3MBTL1KDM1ASLC6A4RCOR1 | |
| SCHEMBL641471 | 0.77 | POLB (0.49) | HTR2CL3MBTL1KDM1ARCOR1EPHX2 | |
| SCHEMBL1580354 | 0.76 | HTR2C (0.41) | HTR2CL3MBTL1KDM1ARCOR1EPHX1 | |
| SCHEMBL23390296 | 0.73 | LIPE (0.52) | HTR2CEPHX1EPHX2 | |
| SCHEMBL27819225 | 0.72 | HTR2C (0.40) | HTR2CL3MBTL1KDM1ASLC6A4RCOR1 | |
| Hydrochloric Acid SCHEMBL23390064 | 0.72 | LIPE (0.51) | HTR2CEPHX1EPHX2 | |
| Hydrochloric Acid SCHEMBL23390063 | 0.72 | LIPE (0.51) | HTR2CEPHX1EPHX2 | |
| SCHEMBL640587 | 0.71 | HTR2C (0.42) | HTR2CEPHX2 | |
| SCHEMBL2929269 | 0.71 | EPHX2 (0.44) | HTR2CEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |